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3β-Chloro-6-[2-(2-cyanoacetyl)hydrazin-1-ylidene]-5α-cholestane
The asymmetric unit of the title compound, C(30)H(48)ClN(3)O, contains two molecules, A and B. In both molecules, the three cyclohexane rings in the steroid fused ring systems adopt chair conformations, while the cyclopentane rings adopt envelope and twist conformations in molecules A and B, re...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344016/ https://www.ncbi.nlm.nih.gov/pubmed/22589925 http://dx.doi.org/10.1107/S1600536812009336 |
Sumario: | The asymmetric unit of the title compound, C(30)H(48)ClN(3)O, contains two molecules, A and B. In both molecules, the three cyclohexane rings in the steroid fused ring systems adopt chair conformations, while the cyclopentane rings adopt envelope and twist conformations in molecules A and B, respectively. In molecule B, the cyano group is disordered over two orientations with refined site-occupancies of 0.593 (8) and 0.407 (8). An intramolecular C—H⋯N interaction forms an S(10) ring in both molecules. In the crystal, molecules are linked by N—H⋯O, C—H⋯O and C—H⋯N interactions, resulting is chains propagating along the a-axis direction. |
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