4-(4-Amino-2-fluoro­phen­oxy)-7-meth­oxy­quinazolin-6-ol methanol monosolvate

In the title compound, C(15)H(12)FN(3)O(3)·CH(3)OH, the dihedral angle between the quinazoline ring system and the benzene ring is 81.18 (9)°. In the crystal, mol­ecules are linked by N—H⋯O and O—H⋯N hydrogen bonds, generating [10-1] chains of alternating main mol­ecules and solvent mol­ecules. Weak...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Wei, Tan, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344092/
https://www.ncbi.nlm.nih.gov/pubmed/22606095
http://dx.doi.org/10.1107/S1600536812011725
_version_ 1782231913969221632
author Huang, Wei
Tan, Aimin
author_facet Huang, Wei
Tan, Aimin
author_sort Huang, Wei
collection PubMed
description In the title compound, C(15)H(12)FN(3)O(3)·CH(3)OH, the dihedral angle between the quinazoline ring system and the benzene ring is 81.18 (9)°. In the crystal, mol­ecules are linked by N—H⋯O and O—H⋯N hydrogen bonds, generating [10-1] chains of alternating main mol­ecules and solvent mol­ecules. Weak C—H⋯O inter­actions are also observed.
format Online
Article
Text
id pubmed-3344092
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-33440922012-05-17 4-(4-Amino-2-fluoro­phen­oxy)-7-meth­oxy­quinazolin-6-ol methanol monosolvate Huang, Wei Tan, Aimin Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(15)H(12)FN(3)O(3)·CH(3)OH, the dihedral angle between the quinazoline ring system and the benzene ring is 81.18 (9)°. In the crystal, mol­ecules are linked by N—H⋯O and O—H⋯N hydrogen bonds, generating [10-1] chains of alternating main mol­ecules and solvent mol­ecules. Weak C—H⋯O inter­actions are also observed. International Union of Crystallography 2012-03-24 /pmc/articles/PMC3344092/ /pubmed/22606095 http://dx.doi.org/10.1107/S1600536812011725 Text en © Huang and Tan 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Huang, Wei
Tan, Aimin
4-(4-Amino-2-fluoro­phen­oxy)-7-meth­oxy­quinazolin-6-ol methanol monosolvate
title 4-(4-Amino-2-fluoro­phen­oxy)-7-meth­oxy­quinazolin-6-ol methanol monosolvate
title_full 4-(4-Amino-2-fluoro­phen­oxy)-7-meth­oxy­quinazolin-6-ol methanol monosolvate
title_fullStr 4-(4-Amino-2-fluoro­phen­oxy)-7-meth­oxy­quinazolin-6-ol methanol monosolvate
title_full_unstemmed 4-(4-Amino-2-fluoro­phen­oxy)-7-meth­oxy­quinazolin-6-ol methanol monosolvate
title_short 4-(4-Amino-2-fluoro­phen­oxy)-7-meth­oxy­quinazolin-6-ol methanol monosolvate
title_sort 4-(4-amino-2-fluoro­phen­oxy)-7-meth­oxy­quinazolin-6-ol methanol monosolvate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344092/
https://www.ncbi.nlm.nih.gov/pubmed/22606095
http://dx.doi.org/10.1107/S1600536812011725
work_keys_str_mv AT huangwei 44amino2fluorophenoxy7methoxyquinazolin6olmethanolmonosolvate
AT tanaimin 44amino2fluorophenoxy7methoxyquinazolin6olmethanolmonosolvate

Ejemplares similares