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N′-Cyclo­dodecyl­idene­pyridine-4-carbohydrazide

The title compound, C(18)H(27)N(3)O, is a derivative of the anti­tuberculosis drug isoniazid (systematic name: pyridine-4-carbohydrazidei). The crystal structure consists of repeating C(4) chains along the b axis, formed by N—H⋯O hydrogen bonds with adjacent amide functional groups that are related...

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Detalles Bibliográficos
Autores principales: Lemmerer, Andreas, Bernstein, Joel, Kahlenberg, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344142/
https://www.ncbi.nlm.nih.gov/pubmed/22606145
http://dx.doi.org/10.1107/S1600536812011774
Descripción
Sumario:The title compound, C(18)H(27)N(3)O, is a derivative of the anti­tuberculosis drug isoniazid (systematic name: pyridine-4-carbohydrazidei). The crystal structure consists of repeating C(4) chains along the b axis, formed by N—H⋯O hydrogen bonds with adjacent amide functional groups that are related by a b-glide plane. The cyclo­dodecyl ring has the same approximately ‘square’ conformation, as seen in the parent hydro­carbon cyclo­dodecane.