N′-Cyclo­dodecyl­idene­pyridine-4-carbohydrazide

The title compound, C(18)H(27)N(3)O, is a derivative of the anti­tuberculosis drug isoniazid (systematic name: pyridine-4-carbohydrazidei). The crystal structure consists of repeating C(4) chains along the b axis, formed by N—H⋯O hydrogen bonds with adjacent amide functional groups that are related...

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Detalles Bibliográficos
Autores principales: Lemmerer, Andreas, Bernstein, Joel, Kahlenberg, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344142/
https://www.ncbi.nlm.nih.gov/pubmed/22606145
http://dx.doi.org/10.1107/S1600536812011774
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author Lemmerer, Andreas
Bernstein, Joel
Kahlenberg, Volker
author_facet Lemmerer, Andreas
Bernstein, Joel
Kahlenberg, Volker
author_sort Lemmerer, Andreas
collection PubMed
description The title compound, C(18)H(27)N(3)O, is a derivative of the anti­tuberculosis drug isoniazid (systematic name: pyridine-4-carbohydrazidei). The crystal structure consists of repeating C(4) chains along the b axis, formed by N—H⋯O hydrogen bonds with adjacent amide functional groups that are related by a b-glide plane. The cyclo­dodecyl ring has the same approximately ‘square’ conformation, as seen in the parent hydro­carbon cyclo­dodecane.
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spelling pubmed-33441422012-05-17 N′-Cyclo­dodecyl­idene­pyridine-4-carbohydrazide Lemmerer, Andreas Bernstein, Joel Kahlenberg, Volker Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(18)H(27)N(3)O, is a derivative of the anti­tuberculosis drug isoniazid (systematic name: pyridine-4-carbohydrazidei). The crystal structure consists of repeating C(4) chains along the b axis, formed by N—H⋯O hydrogen bonds with adjacent amide functional groups that are related by a b-glide plane. The cyclo­dodecyl ring has the same approximately ‘square’ conformation, as seen in the parent hydro­carbon cyclo­dodecane. International Union of Crystallography 2012-03-28 /pmc/articles/PMC3344142/ /pubmed/22606145 http://dx.doi.org/10.1107/S1600536812011774 Text en © Lemmerer et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Lemmerer, Andreas
Bernstein, Joel
Kahlenberg, Volker
N′-Cyclo­dodecyl­idene­pyridine-4-carbohydrazide
title N′-Cyclo­dodecyl­idene­pyridine-4-carbohydrazide
title_full N′-Cyclo­dodecyl­idene­pyridine-4-carbohydrazide
title_fullStr N′-Cyclo­dodecyl­idene­pyridine-4-carbohydrazide
title_full_unstemmed N′-Cyclo­dodecyl­idene­pyridine-4-carbohydrazide
title_short N′-Cyclo­dodecyl­idene­pyridine-4-carbohydrazide
title_sort n′-cyclo­dodecyl­idene­pyridine-4-carbohydrazide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344142/
https://www.ncbi.nlm.nih.gov/pubmed/22606145
http://dx.doi.org/10.1107/S1600536812011774
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