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N-Cyclo­hexyl-N-{[3-(4,6-dimeth­oxy­pyrimidin-2-yl­oxy)pyridin-2-yl]meth­yl}4,6-dimeth­oxy­pyrimidin-2-amine

In the title compound, C(24)H(30)N(6)O(5), the cyclo­hexyl ring adopts a chair conformation, while the remainder of the mol­ecule adopts a U-shape. The dihedral angles between the pyridine ring and the pendant pyrimidine rings are 69.04 (12) and 75.99 (9)°. The two pyrimidine rings, however, are nea...

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Autores principales: Wang, De-Cai, Wang, Yu-Jing, Song, Jun-Song, Wei, Ping, Ou-yang, Ping-Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344196/
https://www.ncbi.nlm.nih.gov/pubmed/22606199
http://dx.doi.org/10.1107/S1600536812013104
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author Wang, De-Cai
Wang, Yu-Jing
Song, Jun-Song
Wei, Ping
Ou-yang, Ping-Kai
author_facet Wang, De-Cai
Wang, Yu-Jing
Song, Jun-Song
Wei, Ping
Ou-yang, Ping-Kai
author_sort Wang, De-Cai
collection PubMed
description In the title compound, C(24)H(30)N(6)O(5), the cyclo­hexyl ring adopts a chair conformation, while the remainder of the mol­ecule adopts a U-shape. The dihedral angles between the pyridine ring and the pendant pyrimidine rings are 69.04 (12) and 75.99 (9)°. The two pyrimidine rings, however, are nearly parallel to one another, with a dihedral angle of 8.56 (15)° between them. They are also involved in an intra­molecular π–π stacking inter­action with a distance of 3.6627 (18) Å between the ring centroids. In the crystal, C—H⋯O contacts link the mol­ecules into chains along the b axis.
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spelling pubmed-33441962012-05-17 N-Cyclo­hexyl-N-{[3-(4,6-dimeth­oxy­pyrimidin-2-yl­oxy)pyridin-2-yl]meth­yl}4,6-dimeth­oxy­pyrimidin-2-amine Wang, De-Cai Wang, Yu-Jing Song, Jun-Song Wei, Ping Ou-yang, Ping-Kai Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(24)H(30)N(6)O(5), the cyclo­hexyl ring adopts a chair conformation, while the remainder of the mol­ecule adopts a U-shape. The dihedral angles between the pyridine ring and the pendant pyrimidine rings are 69.04 (12) and 75.99 (9)°. The two pyrimidine rings, however, are nearly parallel to one another, with a dihedral angle of 8.56 (15)° between them. They are also involved in an intra­molecular π–π stacking inter­action with a distance of 3.6627 (18) Å between the ring centroids. In the crystal, C—H⋯O contacts link the mol­ecules into chains along the b axis. International Union of Crystallography 2012-03-31 /pmc/articles/PMC3344196/ /pubmed/22606199 http://dx.doi.org/10.1107/S1600536812013104 Text en © Wang et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Wang, De-Cai
Wang, Yu-Jing
Song, Jun-Song
Wei, Ping
Ou-yang, Ping-Kai
N-Cyclo­hexyl-N-{[3-(4,6-dimeth­oxy­pyrimidin-2-yl­oxy)pyridin-2-yl]meth­yl}4,6-dimeth­oxy­pyrimidin-2-amine
title N-Cyclo­hexyl-N-{[3-(4,6-dimeth­oxy­pyrimidin-2-yl­oxy)pyridin-2-yl]meth­yl}4,6-dimeth­oxy­pyrimidin-2-amine
title_full N-Cyclo­hexyl-N-{[3-(4,6-dimeth­oxy­pyrimidin-2-yl­oxy)pyridin-2-yl]meth­yl}4,6-dimeth­oxy­pyrimidin-2-amine
title_fullStr N-Cyclo­hexyl-N-{[3-(4,6-dimeth­oxy­pyrimidin-2-yl­oxy)pyridin-2-yl]meth­yl}4,6-dimeth­oxy­pyrimidin-2-amine
title_full_unstemmed N-Cyclo­hexyl-N-{[3-(4,6-dimeth­oxy­pyrimidin-2-yl­oxy)pyridin-2-yl]meth­yl}4,6-dimeth­oxy­pyrimidin-2-amine
title_short N-Cyclo­hexyl-N-{[3-(4,6-dimeth­oxy­pyrimidin-2-yl­oxy)pyridin-2-yl]meth­yl}4,6-dimeth­oxy­pyrimidin-2-amine
title_sort n-cyclo­hexyl-n-{[3-(4,6-dimeth­oxy­pyrimidin-2-yl­oxy)pyridin-2-yl]meth­yl}4,6-dimeth­oxy­pyrimidin-2-amine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344196/
https://www.ncbi.nlm.nih.gov/pubmed/22606199
http://dx.doi.org/10.1107/S1600536812013104
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