Cargando…

Response Surface Methodology to Optimize Enzymatic Preparation of Deapio-Platycodin D and Platycodin D from Radix Platycodi

In the present work, we reported the enzymatic preparation of deapio-platycodin D (dPD) and platycodin D (PD) optimized by response surface methodology (RSM) from Radix Platycodi. During investigation of the hydrolysis of crude platycosides by various glycoside hydrolases, snailase showed a strong a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Wei, Zhao, Li-Chun, Wang, Zi, Zheng, Yi-Nan, Liang, Jian, Wang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344203/ https://www.ncbi.nlm.nih.gov/pubmed/22605967 http://dx.doi.org/10.3390/ijms13044089

Ejemplares similares

Pharmacokinetics, intestinal absorption and microbial metabolism of single platycodin D in comparison to Platycodi radix extract
por: Shan, Jinjun, et al.
Publicado: (2015)

Single Oral Dose Toxicity Test of Platycodin D, a Saponin from Platycodin Radix in Mice
por: Lee, Won-Ho, et al.
Publicado: (2011)

The Effects of Platycodin D, a Saponin Purified from Platycodi Radix, on Collagen-Induced DBA/1J Mouse Rheumatoid Arthritis
por: Kwon, O. Gon, et al.
Publicado: (2014)

In Vivo and In Vitro Antitumor Effects of Platycodin D, a Saponin Purified from Platycodi Radix on the H520 Lung Cancer Cell
por: Park, Jae Chan, et al.
Publicado: (2014)

Determination of Platycodin D and Platycodin D3 in Rat Plasma Using Liquid Chromatography-Tandem Mass Spectrometry
por: Kim, Tae-Hyun, et al.
Publicado: (2014)

Biocatalysis of Platycoside E and Platycodin D3 Using Fungal Extracellular β-Glucosidase Responsible for Rapid Platycodin D Production
por: Ahn, Hyung Jin, et al.
Publicado: (2018)

Establishment of indirect competitive enzyme-linked immunosorbent assay for the detection of platycodin D in Radix Platycodonis
por: Luo, Shuai, et al.
Publicado: (2020)

Killing cancer with platycodin D through multiple mechanisms
por: Khan, Muhammad, et al.
Publicado: (2015)

The pharmacology and mechanisms of platycodin D, an active triterpenoid saponin from Platycodon grandiflorus
por: Xie, Long, et al.
Publicado: (2023)

Enzymatic Biotransformation of Balloon Flower Root Saponins into Bioactive Platycodin D by Deglucosylation with Caldicellulosiruptor bescii β-Glucosidase
por: Kil, Tae-Geun, et al.
Publicado: (2019)

Platycodin D from Platycodonis Radix enhances the anti-proliferative effects of doxorubicin on breast cancer MCF-7 and MDA-MB-231 cells
por: Tang, Zheng-Hai, et al.
Publicado: (2014)

Effects of Platycodin D on Reflux Esophagitis due to Modulation of Antioxidant Defense Systems
por: Cho, Su-Yeon, et al.
Publicado: (2018)

Adjuvant Effects of Platycodin D on Immune Responses to Infectious Bronchitis Vaccine in Chickens
por: Zhou, Yefei, et al.
Publicado: (2020)

Tumor-targeted liposomes with platycodin D2 promote apoptosis in colorectal cancer
por: Cho, Euni, et al.
Publicado: (2023)

Evaluation of the Spermicidal and Contraceptive Activity of Platycodin D, a Saponin from Platycodon grandiflorum
por: Lu, Zongliang, et al.
Publicado: (2013)

Optimization of extraction condition for platycodin D from Platycodon grandiflorum root and verification of its biological activity
por: Jung, Jihyeon, et al.
Publicado: (2023)

Conversion of Glycosylated Platycoside E to Deapiose-Xylosylated Platycodin D by Cytolase PCL5
por: Shin, Kyung-Chul, et al.
Publicado: (2020)

Platycodin D inhibits autophagy and increases glioblastoma cell death via LDLR upregulation
por: Lee, Sol Ji, et al.
Publicado: (2021)

Effects of Platycodin D on apoptosis, migration, invasion and cell cycle arrest of gallbladder cancer cells
por: Zhang, Xiaoyu, et al.
Publicado: (2020)

Combined Anti-Cancer Effects of Platycodin D and Sorafenib on Androgen-Independent and PTEN-Deficient Prostate Cancer
por: Lu, Zongliang, et al.
Publicado: (2021)

Caspase-1-Dependent Pyroptosis Mediates Adjuvant Activity of Platycodin D as an Adjuvant for Intramuscular Vaccines
por: Zhu, Liyan, et al.
Publicado: (2022)

Platycodin D inhibits platelet function and thrombus formation through inducing internalization of platelet glycoprotein receptors
por: Luo, Qi, et al.
Publicado: (2018)

Molecular Cloning and Functional Characterization of a β-Glucosidase Gene to Produce Platycodin D in Platycodon grandiflorus
por: Su, Xinglong, et al.
Publicado: (2022)

Whole Transcriptome Analysis Identifies Platycodin D-Mediated RNA Regulatory Network in Non–Small-Cell Lung Cancer
por: Zheng, Shuyu, et al.
Publicado: (2022)

Platycodin-D exerts its anti-cancer effect by promoting c-Myc protein ubiquitination and degradation in gastric cancer
por: Xu, Qianqian, et al.
Publicado: (2023)

A safety study on ultra‑high or moderate static magnetic fields combined with platycodin D against lung cancer
por: Yang, Xingxing, et al.
Publicado: (2023)

Platycodin D, a bioactive component of Platycodon grandiflorum, induces cancer cell death associated with extreme vacuolation
por: Jeon, Daun, et al.
Publicado: (2019)

Platycodin D Suppresses Type 2 Porcine Reproductive and Respiratory Syndrome Virus In Primary and Established Cell Lines
por: Zhang, Mingxin, et al.
Publicado: (2018)

Platycodin D confers oxaliplatin Resistance in Colorectal Cancer by activating the LATS2/YAP1 axis of the hippo signaling pathway
por: Wang, Chien-Hao, et al.
Publicado: (2023)

The inhibition of Platycodin D on Mycoplasma pneumoniae proliferation and its effect on promoting cell growth after anti-Mycoplasma pneumoniae treatment
por: Meng, Yanli, et al.
Publicado: (2015)

Effects of Platycodin D on Proliferation, Apoptosis and PI3K/Akt Signal Pathway of Human Glioma U251 Cells
por: Xu, Chong, et al.
Publicado: (2014)

Platycodin D regulates high glucose-induced ferroptosis of HK-2 cells through glutathione peroxidase 4 (GPX4)
por: Huang, Jinzhong, et al.
Publicado: (2022)

Platycodin D Induces Tumor Growth Arrest by Activating FOXO3a Expression in Prostate Cancer in vitro and in vivo
por: Zhou, Rui, et al.
Publicado: (2014)

Platycodin D enhances LDLR expression and LDL uptake via down-regulation of IDOL mRNA in hepatic cells
por: Choi, Yu-Jeong, et al.
Publicado: (2020)

Platycodin D inhibits the proliferation and migration of hypertrophic scar-derived fibroblasts and promotes apoptosis through a caspase-dependent pathway
por: Yu, Zhencheng, et al.
Publicado: (2022)

Platycodin D sensitizes KRAS-mutant colorectal cancer cells to cetuximab by inhibiting the PI3K/Akt signaling pathway
por: Liu, Yanfei, et al.
Publicado: (2022)

A candidate gene identified in converting platycoside E to platycodin D from Platycodon grandiflorus by transcriptome and main metabolites analysis
por: Su, Xinglong, et al.
Publicado: (2021)

Protective Effects of Platycodin D on Lipopolysaccharide-Induced Acute Lung Injury by Activating LXRα–ABCA1 Signaling Pathway
por: Hu, Xiaoyu, et al.
Publicado: (2017)

Platycodin D Inhibits Inflammatory Response in LPS-Stimulated Primary Rat Microglia Cells through Activating LXRα–ABCA1 Signaling Pathway
por: Fu, Yunhe, et al.
Publicado: (2018)

Effects of Platycodins Folium on Depression in Mice Based on a UPLC-Q/TOF-MS Serum Assay and Hippocampus Metabolomics
por: Wang, Cuizhu, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_54q4l67iq001cs1daf4fcf2qcd