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Diethyl 4-[5-(4-chloro­phen­yl)-1H-pyrazol-4-yl]-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate

In the title compound, C(22)H(24)ClN(3)O(4), intra­molecular C—H⋯O and C—H⋯N hydrogen bonds form S(9) and S(7) ring motifs, respectively. The 1,4-dihydro­pyridine ring adopts a flattened boat conformation. The benzene ring makes a dihedral angle of 33.36 (6)° with the pyrazole ring. In the crystal,...

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Autores principales: Fun, Hoong-Kun, Loh, Wan-Sin, Vijesh, A. M., Isloor, Arun M., Malladi, Shridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344438/
https://www.ncbi.nlm.nih.gov/pubmed/22590200
http://dx.doi.org/10.1107/S160053681201344X
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author Fun, Hoong-Kun
Loh, Wan-Sin
Vijesh, A. M.
Isloor, Arun M.
Malladi, Shridhar
author_facet Fun, Hoong-Kun
Loh, Wan-Sin
Vijesh, A. M.
Isloor, Arun M.
Malladi, Shridhar
author_sort Fun, Hoong-Kun
collection PubMed
description In the title compound, C(22)H(24)ClN(3)O(4), intra­molecular C—H⋯O and C—H⋯N hydrogen bonds form S(9) and S(7) ring motifs, respectively. The 1,4-dihydro­pyridine ring adopts a flattened boat conformation. The benzene ring makes a dihedral angle of 33.36 (6)° with the pyrazole ring. In the crystal, pairs of N—H⋯N hydrogen bonds link the mol­ecules into inversion dimers. The dimers are stacked in column along the a axis through N—H⋯O and C—H⋯N hydrogen bonds. The crystal packing also features C—H⋯π inter­actions involving the pyrazole ring.
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spelling pubmed-33444382012-05-15 Diethyl 4-[5-(4-chloro­phen­yl)-1H-pyrazol-4-yl]-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate Fun, Hoong-Kun Loh, Wan-Sin Vijesh, A. M. Isloor, Arun M. Malladi, Shridhar Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(22)H(24)ClN(3)O(4), intra­molecular C—H⋯O and C—H⋯N hydrogen bonds form S(9) and S(7) ring motifs, respectively. The 1,4-dihydro­pyridine ring adopts a flattened boat conformation. The benzene ring makes a dihedral angle of 33.36 (6)° with the pyrazole ring. In the crystal, pairs of N—H⋯N hydrogen bonds link the mol­ecules into inversion dimers. The dimers are stacked in column along the a axis through N—H⋯O and C—H⋯N hydrogen bonds. The crystal packing also features C—H⋯π inter­actions involving the pyrazole ring. International Union of Crystallography 2012-04-04 /pmc/articles/PMC3344438/ /pubmed/22590200 http://dx.doi.org/10.1107/S160053681201344X Text en © Fun et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Fun, Hoong-Kun
Loh, Wan-Sin
Vijesh, A. M.
Isloor, Arun M.
Malladi, Shridhar
Diethyl 4-[5-(4-chloro­phen­yl)-1H-pyrazol-4-yl]-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title Diethyl 4-[5-(4-chloro­phen­yl)-1H-pyrazol-4-yl]-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title_full Diethyl 4-[5-(4-chloro­phen­yl)-1H-pyrazol-4-yl]-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title_fullStr Diethyl 4-[5-(4-chloro­phen­yl)-1H-pyrazol-4-yl]-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title_full_unstemmed Diethyl 4-[5-(4-chloro­phen­yl)-1H-pyrazol-4-yl]-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title_short Diethyl 4-[5-(4-chloro­phen­yl)-1H-pyrazol-4-yl]-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title_sort diethyl 4-[5-(4-chloro­phen­yl)-1h-pyrazol-4-yl]-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344438/
https://www.ncbi.nlm.nih.gov/pubmed/22590200
http://dx.doi.org/10.1107/S160053681201344X
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