5-Bromo-N-(3,4-dimeth­oxy­benz­yl)pyridin-2-amine

The title compound, C(14)H(15)BrN(2)O(2), an inter­mediate in drug discovery, was synthesized by the reaction of 5-bromo­pyridin-2-amine and 3,4-dimeth­oxy­benzaldehyde. In the crystal, molecules are linked via pairs ofN—H⋯N hydrogen bonds, leading to the formation of inversion dimers. A short conta...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jie, Lu, Lin-Yan, Shen, Wang-Xing, Shi, Jian-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344531/
https://www.ncbi.nlm.nih.gov/pubmed/22590293
http://dx.doi.org/10.1107/S1600536812015796
Descripción
Sumario:The title compound, C(14)H(15)BrN(2)O(2), an inter­mediate in drug discovery, was synthesized by the reaction of 5-bromo­pyridin-2-amine and 3,4-dimeth­oxy­benzaldehyde. In the crystal, molecules are linked via pairs ofN—H⋯N hydrogen bonds, leading to the formation of inversion dimers. A short contact occurs between the aryl H atom (ortho position from N) and the centroid of the benzene ring.

Ejemplares similares