5-Bromo-N-(3,4-dimeth­oxy­benz­yl)pyridin-2-amine

The title compound, C(14)H(15)BrN(2)O(2), an inter­mediate in drug discovery, was synthesized by the reaction of 5-bromo­pyridin-2-amine and 3,4-dimeth­oxy­benzaldehyde. In the crystal, molecules are linked via pairs ofN—H⋯N hydrogen bonds, leading to the formation of inversion dimers. A short conta...

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Detalles Bibliográficos
Autores principales: Li, Jie, Lu, Lin-Yan, Shen, Wang-Xing, Shi, Jian-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344531/
https://www.ncbi.nlm.nih.gov/pubmed/22590293
http://dx.doi.org/10.1107/S1600536812015796
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author Li, Jie
Lu, Lin-Yan
Shen, Wang-Xing
Shi, Jian-You
author_facet Li, Jie
Lu, Lin-Yan
Shen, Wang-Xing
Shi, Jian-You
author_sort Li, Jie
collection PubMed
description The title compound, C(14)H(15)BrN(2)O(2), an inter­mediate in drug discovery, was synthesized by the reaction of 5-bromo­pyridin-2-amine and 3,4-dimeth­oxy­benzaldehyde. In the crystal, molecules are linked via pairs ofN—H⋯N hydrogen bonds, leading to the formation of inversion dimers. A short contact occurs between the aryl H atom (ortho position from N) and the centroid of the benzene ring.
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spelling pubmed-33445312012-05-15 5-Bromo-N-(3,4-dimeth­oxy­benz­yl)pyridin-2-amine Li, Jie Lu, Lin-Yan Shen, Wang-Xing Shi, Jian-You Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(14)H(15)BrN(2)O(2), an inter­mediate in drug discovery, was synthesized by the reaction of 5-bromo­pyridin-2-amine and 3,4-dimeth­oxy­benzaldehyde. In the crystal, molecules are linked via pairs ofN—H⋯N hydrogen bonds, leading to the formation of inversion dimers. A short contact occurs between the aryl H atom (ortho position from N) and the centroid of the benzene ring. International Union of Crystallography 2012-04-18 /pmc/articles/PMC3344531/ /pubmed/22590293 http://dx.doi.org/10.1107/S1600536812015796 Text en © Li et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Li, Jie
Lu, Lin-Yan
Shen, Wang-Xing
Shi, Jian-You
5-Bromo-N-(3,4-dimeth­oxy­benz­yl)pyridin-2-amine
title 5-Bromo-N-(3,4-dimeth­oxy­benz­yl)pyridin-2-amine
title_full 5-Bromo-N-(3,4-dimeth­oxy­benz­yl)pyridin-2-amine
title_fullStr 5-Bromo-N-(3,4-dimeth­oxy­benz­yl)pyridin-2-amine
title_full_unstemmed 5-Bromo-N-(3,4-dimeth­oxy­benz­yl)pyridin-2-amine
title_short 5-Bromo-N-(3,4-dimeth­oxy­benz­yl)pyridin-2-amine
title_sort 5-bromo-n-(3,4-dimeth­oxy­benz­yl)pyridin-2-amine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344531/
https://www.ncbi.nlm.nih.gov/pubmed/22590293
http://dx.doi.org/10.1107/S1600536812015796
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AT lulinyan 5bromon34dimethoxybenzylpyridin2amine
AT shenwangxing 5bromon34dimethoxybenzylpyridin2amine
AT shijianyou 5bromon34dimethoxybenzylpyridin2amine

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