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Tizoxanide pyridine monosolvate
In the title compound [systematic name: 2-hydroxy-N-(5-nitro-1,3-thiazol-2-yl)benzamide pyridine monosolvate], C(10)H(7)N(3)O(4)S·C(5)H(5)N, the dihedral angle between the pyridine and benzamide rings is 80.55 (7)°. An intamolecular O—H⋯N hydrogen bond occurs in the tizoxanide. In the crystal, the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344569/ https://www.ncbi.nlm.nih.gov/pubmed/22590331 http://dx.doi.org/10.1107/S1600536812016133 |
Sumario: | In the title compound [systematic name: 2-hydroxy-N-(5-nitro-1,3-thiazol-2-yl)benzamide pyridine monosolvate], C(10)H(7)N(3)O(4)S·C(5)H(5)N, the dihedral angle between the pyridine and benzamide rings is 80.55 (7)°. An intamolecular O—H⋯N hydrogen bond occurs in the tizoxanide. In the crystal, the components are linked by an O–H⋯N hydrogen bond, forming a zigzag chain along the c axis. Aromatic π–π interactions between inversion-related pyridine rings [centroid–centroid distance = 3.803 (6) Å] are also observed. |
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