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Tizoxanide pyridine monosolvate

In the title compound [systematic name: 2-hy­droxy-N-(5-nitro-1,3-thia­zol-2-yl)benzamide pyridine monosolvate], C(10)H(7)N(3)O(4)S·C(5)H(5)N, the dihedral angle between the pyridine and benzamide rings is 80.55 (7)°. An intamolecular O—H⋯N hydrogen bond occurs in the tizoxanide. In the crystal, the...

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Detalles Bibliográficos
Autores principales: Zheng, Huaqin, Deng, Hui, Chen, Yunyun, Li, Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344569/
https://www.ncbi.nlm.nih.gov/pubmed/22590331
http://dx.doi.org/10.1107/S1600536812016133
Descripción
Sumario:In the title compound [systematic name: 2-hy­droxy-N-(5-nitro-1,3-thia­zol-2-yl)benzamide pyridine monosolvate], C(10)H(7)N(3)O(4)S·C(5)H(5)N, the dihedral angle between the pyridine and benzamide rings is 80.55 (7)°. An intamolecular O—H⋯N hydrogen bond occurs in the tizoxanide. In the crystal, the components are linked by an O–H⋯N hydrogen bond, forming a zigzag chain along the c axis. Aromatic π–π inter­actions between inversion-related pyridine rings [centroid–centroid distance = 3.803 (6) Å] are also observed.