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Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage
BACKGROUND: Inflammatory injury plays a critical role in intracerebral hemorrhage (ICH)-induced neurological deficits; however, the signaling pathways are not apparent by which the upstream cellular events trigger innate immune and inflammatory responses that contribute to neurological impairments....
Autores principales: | Lin, Sen, Yin, Qing, Zhong, Qi, Lv, Feng-Lin, Zhou, Yu, Li, Jing-Qi, Wang, Jing-Zhou, Su, Bing-yin, Yang, Qing-Wu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344687/ https://www.ncbi.nlm.nih.gov/pubmed/22394415 http://dx.doi.org/10.1186/1742-2094-9-46 |
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