Cargando…

Studies on HIV integrase-LEDGF/p75 interaction inhibitory activity of isatine derivative using the alpha screen luminescent proximity assay

Detalles Bibliográficos
Autor principal:	Selvam, Periyasamy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Oral Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344761/ http://dx.doi.org/10.1186/1471-2334-12-S1-O5

Ejemplares similares

Analysis of LEDGF/p75 expression regulation
por: Desfarges, Sébastien, et al.
Publicado: (2009)

LEDGF/p75 is critical but not essential for multiple-round HIV 1 replication
por: Schrijvers, RLG, et al.
Publicado: (2010)

The selenium-containing drug ebselen potently disrupts LEDGF/p75-HIV-1 integrase interaction by targeting LEDGF/p75
por: Zhang, Da-Wei, et al.
Publicado: (2020)

LEDGF/p75 controls 3D-localization of HIV-1 provirus in the nuclear compartment of infected cells
por: Boll, Annegret, et al.
Publicado: (2013)

Investigation of anti-HIV activity, cytotoxicity and HIV integrase inhibitory activity of polyherbal formulation BH extracts
por: Balraj, S, et al.
Publicado: (2014)

The Lentiviral Integrase Binding Protein LEDGF/p75 and HIV-1 Replication
por: Engelman, Alan, et al.
Publicado: (2008)

Modulation of the intrinsic chromatin binding property of HIV-1 integrase by LEDGF/p75
por: Lapaillerie, Delphine, et al.
Publicado: (2021)

HIV-1 integrase modulates the interaction of the HIV-1 cellular cofactor LEDGF/p75 with chromatin
por: Astiazaran, Paulina, et al.
Publicado: (2011)

LEDGF/p75 interacts with divergent lentiviral integrases and modulates their enzymatic activity in vitro
por: Cherepanov, Peter
Publicado: (2007)

A Novel Assay for Screening Inhibitors Targeting HIV Integrase LEDGF/p75 Interaction Based on Ni(2+) Coated Magnetic Agarose Beads
por: Dawei, Zhang, et al.
Publicado: (2016)

LEDGIN-mediated Inhibition of Integrase–LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV
por: Vranckx, Lenard S., et al.
Publicado: (2016)

Characterization of the HIV-1 integrase chromatin- and LEDGF/p75-binding abilities by mutagenic analysis within the catalytic core domain of integrase
por: Zheng, Yingfeng, et al.
Publicado: (2010)

A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site
por: Maehigashi, Tatsuya, et al.
Publicado: (2021)

HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor
por: Wang, Hao, et al.
Publicado: (2012)

Molecular Modeling Study on the Allosteric Inhibition Mechanism of HIV-1 Integrase by LEDGF/p75 Binding Site Inhibitors
por: Xue, Weiwei, et al.
Publicado: (2014)

Efficient transduction of LEDGF/p75 mutant cells by complementary gain-of-function HIV-1 integrase mutant viruses
por: Wang, Hao, et al.
Publicado: (2014)

Allosteric Integrase Inhibitor Influences on HIV-1 Integration and Roles of LEDGF/p75 and HDGFL2 Host Factors
por: Singh, Parmit Kumar, et al.
Publicado: (2022)

HIV-1 integrase SUMOylation and viral replication
por: Zamborlini, Alessia, et al.
Publicado: (2011)

LEDGF/p75 IN interaction inhibitors: in silico studies of an old target with novel approach
por: Pant, Amit M, et al.
Publicado: (2014)

The Interaction Between Lentiviral Integrase and LEDGF: Structural and Functional Insights
por: Hare, Stephen, et al.
Publicado: (2009)

Evaluation of a flavonoid library for inhibition of interaction of HIV-1 integrase with human LEDGF/p75 towards a structure–activity relationship
por: Yin, Zhi-Hui, et al.
Publicado: (2022)

The LEDGF/p75 Integrase Binding Domain Interactome Contributes to the Survival, Clonogenicity, and Tumorsphere Formation of Docetaxel-Resistant Prostate Cancer Cells
por: Ortiz-Hernandez, Greisha L., et al.
Publicado: (2021)

Peptides derived from the HIV-1 integrase promote HIV-1 infection and multi-integration of viral cDNA in LEDGF/p75-knockdown cells
por: Levin, Aviad, et al.
Publicado: (2010)

HIV-1 IN/Pol recruits LEDGF/p75 into viral particles
por: Desimmie, Belete Ayele, et al.
Publicado: (2015)

LEDGINs, a novel class of antivirals targeting HIV integrase during integration and assembly
por: Debyser, Zeger
Publicado: (2013)

LEDGF/p75 Is Required for an Efficient DNA Damage Response
por: Liedtke, Victoria, et al.
Publicado: (2021)

Correction to: HIV-1 IN/Pol recruits LEDGF/p75 into viral particles
por: Desimmie, Belete Ayele, et al.
Publicado: (2020)

A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75
por: Hare, Stephen, et al.
Publicado: (2009)

Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage
por: Le Rouzic, Erwann, et al.
Publicado: (2013)

Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein
por: Bao, Leyuan, et al.
Publicado: (2017)

Small Molecule Inhibitors of the LEDGF Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design
por: Peat, Thomas S., et al.
Publicado: (2012)

Virus Evolution Reveals an Exclusive Role for LEDGF/p75 in Chromosomal Tethering of HIV
por: Hombrouck, Anneleen, et al.
Publicado: (2007)

LEDGF/p75 Proteins with Alternative Chromatin Tethers Are Functional HIV-1 Cofactors
por: Meehan, Anne M., et al.
Publicado: (2009)

Characterization of LEDGF/p75 Genetic Variants and Association with HIV-1 Disease Progression
por: Messiaen, Peter, et al.
Publicado: (2012)

LEDGF/p75 Deficiency Increases Deletions at the HIV-1 cDNA Ends
por: Bueno, Murilo T. D., et al.
Publicado: (2017)

Persistent production of an integrase-deleted HIV-1 variant with no resistance mutation and wild-type proviral DNA in a treated patient
por: Trabaud, MA, et al.
Publicado: (2014)

An Unusual Helix Turn Helix Motif in the Catalytic Core of HIV-1 Integrase Binds Viral DNA and LEDGF
por: Merad, Hayate, et al.
Publicado: (2009)

Activity of the integrase inhibitor S/GSK1349572 in subjects with HIV exhibiting raltegravir resistance: week 24 results of the VIKING study (ING112961)
por: Eron, J, et al.
Publicado: (2010)

Correction: Small Molecule Inhibitors of the LEDGF Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design
por: Peat, Thomas S., et al.
Publicado: (2013)

Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity
por: Tocco, Graziella, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5gcrkina48t9dl2aumscefeh3u