Cargando…
The Threonine Protease Activity of Testes-Specific Protease 50 (TSP50) Is Essential for Its Function in Cell Proliferation
BACKGROUND: Testes-specific protease 50 (TSP50), a newly discovered threonine enzyme, has similar amino acid sequences and enzymatic structures to those of many serine proteases. It may be an oncogene. TSP50 is up-regulated in breast cancer epithelial cells, and ectopic expression of TSP50 in TSP50-...
Autores principales: | Li, Yu-Yin, Bao, Yong-Li, Song, Zhen-Bo, Sun, Lu-Guo, Wu, Ping, Zhang, Yu, Fan, Cong, Huang, Yan-Xin, Wu, Yin, Yu, Chun-Lei, Sun, Ying, Zheng, Li-Hua, Wang, Guan-Nan, Li, Yu-Xin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344824/ https://www.ncbi.nlm.nih.gov/pubmed/22574111 http://dx.doi.org/10.1371/journal.pone.0035030 |
Ejemplares similares
-
Testes-specific protease 50 (TSP50) promotes invasion and metastasis by inducing EMT in gastric cancer
por: Cao, Qing-Hua, et al.
Publicado: (2018) -
Overexpression of Testes-Specific Protease 50 (TSP50) Predicts Poor Prognosis in Patients with Gastric Cancer
por: Liu, Fang, et al.
Publicado: (2014) -
Protumoral TSP50 Regulates Macrophage Activities and Polarization via Production of TNF-α and IL-1β, and Activation of the NF-κB Signaling Pathway
por: Yang, Cheng, et al.
Publicado: (2015) -
TSP50 promotes the Warburg effect and hepatocyte proliferation via regulating PKM2 acetylation
por: Gao, Feng, et al.
Publicado: (2021) -
TSP50 promotes hepatocyte proliferation and tumour formation by activating glucose‐6‐phosphate dehydrogenase (G6PD)
por: Zhang, Xiaojun, et al.
Publicado: (2021)