Cargando…

Interferon-γ Activates Nuclear Factor-κ B in Oligodendrocytes through a Process Mediated by the Unfolded Protein Response

Our previous studies have demonstrated that the effects of the immune cytokine interferon-γ (IFN-γ) in immune-mediated demyelinating diseases are mediated, at least in part, by the unfolded protein response (UPR) in oligodendrocytes. Data indicate that some biological effects of IFN-γ are elicited t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Yifeng, Jamison, Stephanie, Lin, Wensheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344863/ https://www.ncbi.nlm.nih.gov/pubmed/22574154 http://dx.doi.org/10.1371/journal.pone.0036408

Ejemplares similares

Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-γ
por: Lin, Wensheng, et al.
Publicado: (2005)

Pancreatic Endoplasmic Reticulum Kinase Activation Promotes Medulloblastoma Cell Migration and Invasion through Induction of Vascular Endothelial Growth Factor A
por: Jamison, Stephanie, et al.
Publicado: (2015)

Oligodendrocyte-specific ATF4 inactivation does not influence the development of EAE
por: Yue, Yuan, et al.
Publicado: (2019)

Role of nuclear factor κB in multiple sclerosis and experimental autoimmune encephalomyelitis
por: Yue, Yuan, et al.
Publicado: (2018)

Curcumin promotes oligodendrocyte differentiation and their protection against TNF-α through the activation of the nuclear receptor PPAR-γ
por: Bernardo, Antonietta, et al.
Publicado: (2021)

The unfolded protein response in multiple sclerosis
por: Stone, Sarrabeth, et al.
Publicado: (2015)

Unfolded protein response in myelin disorders
por: Lin, Wensheng, et al.
Publicado: (2019)

Binding of interferon reduces the force of unfolding for interferon receptor 1
por: Chuartzman, Silvia G., et al.
Publicado: (2017)

Formosanin C attenuates lipopolysaccharide-induced inflammation through nuclear factor-κB inhibition in macrophages
por: Yin, Limin, et al.
Publicado: (2021)

Nuclear Factor κB (NF-κB)–Mediated Inflammation in Multiple Sclerosis
por: Zhou, Yifan, et al.
Publicado: (2020)

NF-κB is a critical mediator of post-mitotic senescence in oligodendrocytes and subsequent white matter loss
por: Schlett, Judith Stefanie, et al.
Publicado: (2023)

Small Molecule Inhibitors Targeting Nuclear Factor κB Activation Markedly Reduce Expression of Interleukin-2, but Not Interferon-γ, Induced by Phorbol Esters and Calcium Ionophores
por: Tanaka, Yumiko, et al.
Publicado: (2021)

Crosstalk between the Unfolded Protein Response and NF-κB-Mediated Inflammation in the Progression of Chronic Kidney Disease
por: Mohammed-Ali, Zahraa, et al.
Publicado: (2015)

ZHX2 mediates proteasome inhibitor resistance via regulating nuclear translocation of NF‐κB in multiple myeloma
por: Jiang, Jifeng, et al.
Publicado: (2020)

The role of the immunoproteasome in interferon-γ-mediated microglial activation
por: Moritz, Kasey E., et al.
Publicado: (2017)

Insights to Human γD-Crystallin Unfolding by NMR Spectroscopy and Molecular Dynamics Simulations
por: Hsueh, Shu-Shun, et al.
Publicado: (2022)

Nrf2 suppresses lupus nephritis through inhibition of oxidative injury and the NF-κB-mediated inflammatory response
por: Jiang, Tao, et al.
Publicado: (2013)

Role of Glycogen Synthase Kinase-3 in Interferon-γ-Mediated Immune Hepatitis
por: Chen, Chia-Ling, et al.
Publicado: (2022)

The Nuclear Localization of γ-Tubulin Is Regulated by SadB-mediated Phosphorylation
por: Eklund, Greta, et al.
Publicado: (2014)

The Effects of Hesperidin on Neuronal Apoptosis and Cognitive Impairment in the Sevoflurane Anesthetized Rat are Mediated Through the PI3/Akt/PTEN and Nuclear Factor-κB (NF-κB) Signaling Pathways
por: Huang, Haijin, et al.
Publicado: (2020)

Tumor necrosis factor-α and interferon-γ stimulate MUC16 (CA125) expression in breast, endometrial and ovarian cancers through NFκB
por: Morgado, Micaela, et al.
Publicado: (2016)

Adenovirus-mediated delivery of interferon-γ gene inhibits the growth of nasopharyngeal carcinoma
por: Liu, Ran-yi, et al.
Publicado: (2012)

Matricellular Protein Periostin Mediates Intestinal Inflammation through the Activation of Nuclear Factor κB Signaling
por: Koh, Seong-Joon, et al.
Publicado: (2016)

Integration of the Unfolded Protein and Oxidative Stress Responses through SKN-1/Nrf
por: Glover-Cutter, Kira M., et al.
Publicado: (2013)

YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma
por: Rivera-Reyes, Adrian, et al.
Publicado: (2018)

The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina
por: Pruvost, Mathilde, et al.
Publicado: (2023)

Increasing Affinity of Interferon-γ Receptor 1 to Interferon-γ by Computer-Aided Design
por: Mikulecký, Pavel, et al.
Publicado: (2013)

Immunomodulation with Recombinant Interferon-γ1b in Pulmonary Tuberculosis
por: Dawson, Rod, et al.
Publicado: (2009)

Unfolding and modeling the recovery process after COVID lockdowns
por: Yang, Xuan, et al.
Publicado: (2023)

A role of oligodendrocytes in information processing
por: Moore, Sharlen, et al.
Publicado: (2020)

Rel Induces Interferon Regulatory Factor 4 (IRF-4) Expression in Lymphocytes: Modulation of Interferon-Regulated Gene Expression by Rel/Nuclear Factor κB
por: Grumont, Raelene J., et al.
Publicado: (2000)

Elevated NIBP/TRAPPC9 mediates tumorigenesis of cancer cells through NFκB signaling
por: Zhang, Yonggang, et al.
Publicado: (2015)

Inhibitor κBα protein therapy alleviates severe pneumonia through inhibition of nuclear factor κB
por: Xu, Haizhou, et al.
Publicado: (2017)

Interferon-α sensitizes HBx-expressing hepatocarcinoma cells to chemotherapeutic drugs through inhibition of HBx-mediated NF-κB activation
por: Liu, Yanning, et al.
Publicado: (2013)

Interferon γ-Induced Nuclear Interleukin-33 Potentiates the Release of Esophageal Epithelial Derived Cytokines
por: Shan, Jing, et al.
Publicado: (2016)

Malignant germ cell tumours of the testis express interferon-γ, but are resistant to endogenous interferon-γ
por: Schweyer, S, et al.
Publicado: (2003)

Glutamate-mediated effects of caffeine and interferon-γ on mercury-induced toxicity
por: Engin, Ayse Basak, et al.
Publicado: (2017)

Avian Leukosis Virus Subgroup J Attenuates Type I Interferon Production Through Blocking IκB Phosphorylation
por: Lin, Wencheng, et al.
Publicado: (2018)

Interferon-γ Triggers Hepatic Stellate Cell-Mediated Immune Regulation through MEK/ERK Signaling Pathway
por: Gu, Xiaodong, et al.
Publicado: (2013)

Interferon-γ Induces Senescence in Normal Human Melanocytes
por: Wang, Suiquan, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_3knk4oetqenrhnod5ejt5k1dkl