Cargando…

Duloxetine Inhibits Effects of MDMA (“Ecstasy") In Vitro and in Humans in a Randomized Placebo-Controlled Laboratory Study

This study assessed the effects of the serotonin (5-HT) and norepinephrine (NE) transporter inhibitor duloxetine on the effects of 3,4–methylenedioxymethamphetamine (MDMA, ecstasy) in vitro and in 16 healthy subjects. The clinical study used a double-blind, randomized, placebo-controlled, four-sess...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hysek, Cédric M., Simmler, Linda D., Nicola, Valentina G., Vischer, Nerina, Donzelli, Massimiliano, Krähenbühl, Stephan, Grouzmann, Eric, Huwyler, Jörg, Hoener, Marius C., Liechti, Matthias E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344887/ https://www.ncbi.nlm.nih.gov/pubmed/22574166 http://dx.doi.org/10.1371/journal.pone.0036476

Ejemplares similares

Malignant hyperpyrexia in an MDMA ("Ecstasy") abuser.
por: McCoy, E. P., et al.
Publicado: (1994)

Methylenedioxymethamphetamine (MDMA, ‘Ecstasy’): Neurodegeneration versus Neuromodulation
por: Puerta, Elena, et al.
Publicado: (2011)

Ecstasy (MDMA): A rebellion coherent with the system
por: García-Montes, José Manuel, et al.
Publicado: (2020)

Ecstasy (MDMA) and its effects on kidneys and their treatment: a review
por: Bora, Feyza, et al.
Publicado: (2016)

Caffeine and MDMA (Ecstasy) Exacerbate ER Stress Triggered by Hyperthermia
por: Trychta, Kathleen A., et al.
Publicado: (2022)

Neurotoxicity of drugs of abuse - the case of methylenedioxy amphetamines (MDMA, ecstasy ), and amphetamines
por: Gouzoulis-Mayfrank, Euphrosyne, et al.
Publicado: (2009)

A review on the mitochondrial toxicity of “ecstasy” (3,4-methylenedioxymethamphetamine, MDMA)
por: Capela, João Paulo, et al.
Publicado: (2022)

Social Cognition and Interaction in Chronic Users of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”)
por: Wunderli, Michael D, et al.
Publicado: (2017)

Inhibition of mirtazapine metabolism by Ecstasy (MDMA) in isolated perfused rat liver model
por: Jamshidfar, Sanaz, et al.
Publicado: (2017)

Neurochemical and Neurotoxic Effects of MDMA (Ecstasy) and Caffeine After Chronic Combined Administration in Mice
por: Górska, Anna Maria, et al.
Publicado: (2017)

OR17-01 Novel Provocation Test With MDMA (‘Ecstasy’) Reveals Oxytocin Deficiency As A New Pituitary Entity In Patients With Central Diabetes Insipidus - A Randomized Placebo-Controlled Trial
por: Atila, Cihan, et al.
Publicado: (2023)

Exploring functional data analysis and wavelet principal component analysis on ecstasy (MDMA) wastewater data
por: Salvatore, Stefania, et al.
Publicado: (2016)

COMTVal158Met polymorphism is associated with ecstasy (MDMA)-induced psychotic symptoms in the Turkish population
por: Aytac, Hasan Mervan, et al.
Publicado: (2022)

The Effects of Ecstasy (MDMA) on Brain Serotonin Transporters Are Dependent on Age-of-First Exposure in Recreational Users and Animals
por: Klomp, Anne, et al.
Publicado: (2012)

Saturday night fever in ecstasy/MDMA dance clubbers: Heightened body temperature and associated psychobiological changes
por: Parrott, Andrew C, et al.
Publicado: (2014)

Additive Effects of 3,4-Methylenedioxymethamphetamine (MDMA) and Compassionate Imagery on Self-Compassion in Recreational Users of Ecstasy
por: Kamboj, Sunjeev K., et al.
Publicado: (2017)

Erratum to: Exploring functional data analysis and wavelet principal component analysis on ecstasy (MDMA) wastewater data
por: Salvatore, Stefania, et al.
Publicado: (2017)

Associations between MDMA/ecstasy, classic psychedelics, and suicidal thoughts and behaviors in a sample of U.S. adolescents
por: Jones, Grant, et al.
Publicado: (2022)

Chronic exposure to MDMA (Ecstasy) elicits behavioral sensitization in rats but fails to induce cross-sensitization to other psychostimulants
por: Modi, Gunjan M, et al.
Publicado: (2006)

Effects of alcohol (BAC 0.5‰) and ecstasy (MDMA 100 mg) on simulated driving performance and traffic safety
por: Veldstra, Janet L., et al.
Publicado: (2011)

Nephroprotective effects of Feijoa Sellowiana leaves extract on renal injury induced by acute dose of ecstasy (MDMA) in mice
por: Karami, Mohammad, et al.
Publicado: (2014)

Non-Serotonergic Neurotoxicity by MDMA (Ecstasy) in Neurons Derived from Mouse P19 Embryonal Carcinoma Cells
por: Popova, Dina, et al.
Publicado: (2016)

Depressive mood ratings are reduced by MDMA in female polydrug ecstasy users homozygous for the l-allele of the serotonin transporter
por: Kuypers, K. P. C., et al.
Publicado: (2018)

Induced fit, ensemble binding space docking and Monte Carlo simulations of MDMA ‘ecstasy’ and 3D pharmacophore design of MDMA derivatives on the human serotonin transporter (hSERT)
por: Islas, Ángel A., et al.
Publicado: (2021)

Pentoxifylline Protects the Rat Liver Against Fibrosis and Apoptosis Induced by Acute Administration of 3,4-Methylenedioxymethamphetamine (MDMA or Ecstasy)
por: Movassaghi, Shabnam, et al.
Publicado: (2013)

Examining associations between MDMA/ecstasy and classic psychedelic use and impairments in social functioning in a U.S. adult sample
por: Jones, Grant, et al.
Publicado: (2023)

Prediction of MDMA response in healthy humans: a pooled analysis of placebo-controlled studies
por: Studerus, Erich, et al.
Publicado: (2021)

Effects of MDMA on body temperature in humans
por: Liechti, Matthias E
Publicado: (2014)

Tumor targeting using liposomal antineoplastic drugs
por: Huwyler, Jörg, et al.
Publicado: (2008)

MDMA (ecstasy) effects on actual driving performance before and after sleep deprivation, as function of dose and concentration in blood and oral fluid
por: Bosker, Wendy M., et al.
Publicado: (2011)

Aromatic Bromination Abolishes the Psychomotor Features and Pro-social Responses of MDMA (“Ecstasy”) in Rats and Preserves Affinity for the Serotonin Transporter (SERT)
por: Sáez-Briones, Patricio, et al.
Publicado: (2019)

Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”): The Influence of Gender and Genetics (CYP2D6, COMT, 5-HTT)
por: Pardo-Lozano, Ricardo, et al.
Publicado: (2012)

Aromatic Bromination Abolishes Deficits in Visuospatial Learning Induced by MDMA (“Ecstasy”) in Rats While Preserving the Ability to Increase LTP in the Prefrontal Cortex
por: Sáez-Briones, Patricio, et al.
Publicado: (2023)

Death in ecstasy /
por: Marsh, Ngaio, 1895-1982
Publicado: (1962)

Clubbing with ecstasy
por: Kiyatkin, Eugene A, et al.
Publicado: (2014)

Multifaceted empathy of healthy volunteers after single doses of MDMA: A pooled sample of placebo-controlled studies
por: Kuypers, Kim PC, et al.
Publicado: (2017)

No Influence of Dopamine System Gene Variations on Acute Effects of MDMA
por: Vizeli, Patrick, et al.
Publicado: (2019)

Acute effects of MDMA and LSD co-administration in a double-blind placebo-controlled study in healthy participants
por: Straumann, Isabelle, et al.
Publicado: (2023)

Ecstasy and amphetamines : global survey, 2003.
Publicado: (2003)

Modulation of Gut Microbiome in Ecstasy/MDMA-Induced Behavioral and Biochemical Impairment in Rats and Potential of Post-Treatment with Anacyclus pyrethrum L. Aqueous Extract to Mitigate Adverse Effects
por: Baslam, Abdelmounaim, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5t360uhku5qgif8fnto6k9ra8t