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Structural Analyses of the Slm1-PH Domain Demonstrate Ligand Binding in the Non-Canonical Site

BACKGROUND: Pleckstrin homology (PH) domains are common membrane-targeting modules and their best characterized ligands are a set of important signaling lipids that include phosphatidylinositol phosphates (PtdInsPs). PH domains recognize PtdInsPs through two distinct mechanisms that use different bi...

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Detalles Bibliográficos
Autores principales:	Anand, Kanchan, Maeda, Kenji, Gavin, Anne-Claude
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344901/ https://www.ncbi.nlm.nih.gov/pubmed/22574179 http://dx.doi.org/10.1371/journal.pone.0036526

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