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High Throughput Screening for Small Molecule Enhancers of the Interferon Signaling Pathway to Drive Next-Generation Antiviral Drug Discovery
Most of current strategies for antiviral therapeutics target the virus specifically and directly, but an alternative approach to drug discovery might be to enhance the immune response to a broad range of viruses. Based on clinical observation in humans and successful genetic strategies in experiment...
Autores principales: | Patel, Dhara A., Patel, Anand C., Nolan, William C., Zhang, Yong, Holtzman, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344904/ https://www.ncbi.nlm.nih.gov/pubmed/22574190 http://dx.doi.org/10.1371/journal.pone.0036594 |
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