Hypoxia-Adaptation Involves Mitochondrial Metabolic Depression and Decreased ROS Leakage

Through long-term laboratory selection, we have generated a Drosophila melanogaster population that tolerates severe, normally lethal, level of hypoxia. This strain lives perpetually under severe hypoxic conditions (4% O(2)). In order to shed light on the mechanisms involved in this adaptation, we s...

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Detalles Bibliográficos
Autores principales: Ali, Sameh S., Hsiao, Mary, Zhao, Huiwen W., Dugan, Laura L., Haddad, Gabriel G., Zhou, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344937/
https://www.ncbi.nlm.nih.gov/pubmed/22574227
http://dx.doi.org/10.1371/journal.pone.0036801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344937/
https://www.ncbi.nlm.nih.gov/pubmed/22574227
http://dx.doi.org/10.1371/journal.pone.0036801

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