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Hypoxia-Adaptation Involves Mitochondrial Metabolic Depression and Decreased ROS Leakage
Through long-term laboratory selection, we have generated a Drosophila melanogaster population that tolerates severe, normally lethal, level of hypoxia. This strain lives perpetually under severe hypoxic conditions (4% O(2)). In order to shed light on the mechanisms involved in this adaptation, we s...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344937/ https://www.ncbi.nlm.nih.gov/pubmed/22574227 http://dx.doi.org/10.1371/journal.pone.0036801 |