Resveratrol Inhibits Cancer Cell Metabolism by Down Regulating Pyruvate Kinase M2 via Inhibition of Mammalian Target of Rapamycin

Metabolism of cancer cells with pyruvate kinase M2 (PKM2) at its centre stage has assumed a prime significance in cancer research in recent times. Cancer cell metabolism, characterized by enhanced glucose uptake, production of lactate and anabolism is considered an ideal target for therapeutic inter...

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Detalles Bibliográficos
Autores principales: Iqbal, Mohd Askandar, Bamezai, Rameshwar N. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344940/
https://www.ncbi.nlm.nih.gov/pubmed/22574221
http://dx.doi.org/10.1371/journal.pone.0036764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344940/
https://www.ncbi.nlm.nih.gov/pubmed/22574221
http://dx.doi.org/10.1371/journal.pone.0036764

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