Cargando…

TLR Tolerance Reduces IFN-Alpha Production Despite Plasmacytoid Dendritic Cell Expansion and Anti-Nuclear Antibodies in NZB Bicongenic Mice

Genetic loci on New Zealand Black (NZB) chromosomes 1 and 13 play a significant role in the development of lupus-like autoimmune disease. We have previously shown that C57BL/6 (B6) congenic mice with homozygous NZB chromosome 1 (B6.NZBc1) or 13 (B6.NZBc13) intervals develop anti-nuclear antibodies a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pau, Evelyn, Cheung, Yui-Ho, Loh, Christina, Lajoie, Ginette, Wither, Joan E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344944/ https://www.ncbi.nlm.nih.gov/pubmed/22574220 http://dx.doi.org/10.1371/journal.pone.0036761

Ejemplares similares

B Cell Activating Factor (BAFF) and T Cells Cooperate to Breach B Cell Tolerance in Lupus-Prone New Zealand Black (NZB) Mice
por: Chang, Nan-Hua, et al.
Publicado: (2010)

Genetic polymorphisms leading to altered T-cell and dendritic cell function cooperate to produce expansion of proinflammatory T-cell subsets in NZB c1 congenic mice
por: Talaei, N, et al.
Publicado: (2012)

Insights into kidney disease using a bicongenic rat model
Publicado: (2013)

Experimental crescentic glomerulonephritis: a new bicongenic rat model
por: D’Souza, Zelpha, et al.
Publicado: (2013)

HHV-6B Induces IFN-Lambda1 Responses in Cord Plasmacytoid Dendritic Cells through TLR9
por: Nordström, Inger, et al.
Publicado: (2012)

Up-Regulation of TLR7-Mediated IFN-α Production by Plasmacytoid Dendritic Cells in Patients With Systemic Lupus Erythematosus
por: Sakata, Kei, et al.
Publicado: (2018)

Blocking TLR7- and TLR9-mediated IFN-α Production by Plasmacytoid Dendritic Cells Does Not Diminish Immune Activation in Early SIV Infection
por: Kader, Muhamuda, et al.
Publicado: (2013)

An integrin axis induces IFN-β production in plasmacytoid dendritic cells
por: Simoes, Davina Camargo Madeira, et al.
Publicado: (2022)

Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation
por: Gotoh, Kazuhito, et al.
Publicado: (2010)

Lactate Dehydrogenase-Elevating Virus Induces Systemic Lymphocyte Activation via TLR7-Dependent IFNα Responses by Plasmacytoid Dendritic Cells
por: Ammann, Christoph G., et al.
Publicado: (2009)

Sex Differences in Primary HIV Infection: Revisiting the Role of TLR7-Driven Type 1 IFN Production by Plasmacytoid Dendritic Cells in Women
por: Guéry, Jean-Charles
Publicado: (2021)

TRIM8 is required for virus-induced IFN response in human plasmacytoid dendritic cells
por: Maarifi, Ghizlane, et al.
Publicado: (2019)

Activation-induced colocalisation of SCAMP5 with IFNα in human plasmacytoid dendritic cells
por: Pouw, Juliëtte N, et al.
Publicado: (2022)

Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists
por: Birmachu, Woubalem, et al.
Publicado: (2007)

Clonal expansion of abnormal B cells in old NZB mice
Publicado: (1987)

Reduction of IFN-I responses by plasmacytoid dendritic cells in a longitudinal trans men cohort
por: Grünhagel, Benjamin, et al.
Publicado: (2023)

Hepatitis B Virus Impairs TLR9 Expression and Function in Plasmacytoid Dendritic Cells
por: Vincent, Isabelle E., et al.
Publicado: (2011)

BAD-LAMP controls TLR9 trafficking and signalling in human plasmacytoid dendritic cells
por: Combes, Alexis, et al.
Publicado: (2017)

Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9
por: Guiducci, Cristiana, et al.
Publicado: (2010)

MicroRNA-155 Mediates Augmented CD40 Expression in Bone Marrow Derived Plasmacytoid Dendritic Cells in Symptomatic Lupus-Prone NZB/W F1 Mice
por: Yan, Sheng, et al.
Publicado: (2016)

HIV Delays IFN-α Production from Human Plasmacytoid Dendritic Cells and Is Associated with SYK Phosphorylation
por: Lo, Calvin C., et al.
Publicado: (2012)

The MEK1/2-ERK Pathway Inhibits Type I IFN Production in Plasmacytoid Dendritic Cells
por: Janovec, Vaclav, et al.
Publicado: (2018)

The regulation and pharmacological modulation of immune complex induced type III IFN production by plasmacytoid dendritic cells
por: Hjorton, Karin, et al.
Publicado: (2020)

TLR-activated plasmacytoid dendritic cells inhibit breast cancer cell growth in vitro and in vivo
por: Wu, Jing, et al.
Publicado: (2016)

Plasmacytoid Dendritic Cells in Atherosclerosis
por: Döring, Yvonne, et al.
Publicado: (2012)

Plasmacytoid dendritic cells in dermatology()()
por: Dias de Oliveira, Natasha Favoretto, et al.
Publicado: (2021)

Plasmacytoid dendritic cell neoplasms
por: Lee, Yoo Jin, et al.
Publicado: (2023)

In acute pathogenic SIV infection plasmacytoid dendritic cells are depleted from blood and lymph nodes despite mobilization
por: Barratt‐Boyes, Simon M., et al.
Publicado: (2010)

TLR7/TLR8 Activation Restores Defective Cytokine Secretion by Myeloid Dendritic Cells but Not by Plasmacytoid Dendritic Cells in HIV-Infected Pregnant Women and Newborns
por: Cardoso, Elaine Cristina, et al.
Publicado: (2013)

Plasmacytoid Dendritic Cells Contribute to the Production of IFN-β via TLR7-MyD88-Dependent Pathway and CTL Priming during Respiratory Syncytial Virus Infection
por: Kim, Tae Hoon, et al.
Publicado: (2019)

Identification of a lupus-susceptibility locus leading to impaired clearance of apoptotic debris on New Zealand Black chromosome 13
por: Pau, Evelyn, et al.
Publicado: (2013)

Discrepancy in Response of Mouse Dendritic Cells against BCG: Weak Immune Effects of Plasmacytoid Dendritic Cells Compared to Classical Dendritic Cells despite the Uptake of Bacilli
por: Meng, Chuang, et al.
Publicado: (2023)

Rotavirus Structural Proteins and dsRNA Are Required for the Human Primary Plasmacytoid Dendritic Cell IFNα Response
por: Deal, Emily M., et al.
Publicado: (2010)

Plasmacytoid Dendritic Cells Respond Directly to Apoptotic Cells by Secreting Immune Regulatory IL-10 or IFN-α
por: Simpson, Joanne, et al.
Publicado: (2016)

Identification of a novel Dlg2 isoform differentially expressed in IFNβ-producing plasmacytoid dendritic cells
por: Ali, Shafaqat, et al.
Publicado: (2018)

Diminished secretion and function of IL‐29 is associated with impaired IFN‐α response of neonatal plasmacytoid dendritic cells
por: Wisgrill, Lukas, et al.
Publicado: (2019)

TNF-α Regulates Human Plasmacytoid Dendritic Cells by Suppressing IFN-α Production and Enhancing T Cell Activation
por: Psarras, Antonios, et al.
Publicado: (2021)

Phenotypical Diversification of Early IFNα-Producing Human Plasmacytoid Dendritic Cells Using Droplet-Based Microfluidics
por: Van Eyndhoven, Laura C., et al.
Publicado: (2021)

T Cell and Dendritic Cell Abnormalities Synergize to Expand Pro-Inflammatory T Cell Subsets Leading to Fatal Autoimmunity in B6.NZBc1 Lupus-Prone Mice
por: Talaei, Nafiseh, et al.
Publicado: (2013)

Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation
por: Takagi, Hideaki, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_0dt2mm3ghbb4bfn47ucm2ei33s