Nonhuman Primate Induced Pluripotent Stem Cells in Regenerative Medicine

Among the various species from which induced pluripotent stem cells have been derived, nonhuman primates (NHPs) have a unique role as preclinical models. Their relatedness to humans and similar physiology, including central nervous system, make them ideal for translational studies. We review here th...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Yuehong, Mishra, Anuja, Qiu, Zhifang, Farnsworth, Steven, Tardif, Suzette D., Hornsby, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345260/
https://www.ncbi.nlm.nih.gov/pubmed/22577396
http://dx.doi.org/10.1155/2012/767195
_version_ 1782232130342879232
author Wu, Yuehong
Mishra, Anuja
Qiu, Zhifang
Farnsworth, Steven
Tardif, Suzette D.
Hornsby, Peter J.
author_facet Wu, Yuehong
Mishra, Anuja
Qiu, Zhifang
Farnsworth, Steven
Tardif, Suzette D.
Hornsby, Peter J.
author_sort Wu, Yuehong
collection PubMed
description Among the various species from which induced pluripotent stem cells have been derived, nonhuman primates (NHPs) have a unique role as preclinical models. Their relatedness to humans and similar physiology, including central nervous system, make them ideal for translational studies. We review here the progress made in deriving and characterizing iPS cell lines from different NHP species. We focus on iPS cell lines from the marmoset, a small NHP in which several human disease states can be modeled. The marmoset can serve as a model for the implementation of patient-specific autologous cell therapy in regenerative medicine.
format Online
Article
Text
id pubmed-3345260
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-33452602012-05-10 Nonhuman Primate Induced Pluripotent Stem Cells in Regenerative Medicine Wu, Yuehong Mishra, Anuja Qiu, Zhifang Farnsworth, Steven Tardif, Suzette D. Hornsby, Peter J. Stem Cells Int Review Article Among the various species from which induced pluripotent stem cells have been derived, nonhuman primates (NHPs) have a unique role as preclinical models. Their relatedness to humans and similar physiology, including central nervous system, make them ideal for translational studies. We review here the progress made in deriving and characterizing iPS cell lines from different NHP species. We focus on iPS cell lines from the marmoset, a small NHP in which several human disease states can be modeled. The marmoset can serve as a model for the implementation of patient-specific autologous cell therapy in regenerative medicine. Hindawi Publishing Corporation 2012 2012-04-19 /pmc/articles/PMC3345260/ /pubmed/22577396 http://dx.doi.org/10.1155/2012/767195 Text en Copyright © 2012 Yuehong Wu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Wu, Yuehong
Mishra, Anuja
Qiu, Zhifang
Farnsworth, Steven
Tardif, Suzette D.
Hornsby, Peter J.
Nonhuman Primate Induced Pluripotent Stem Cells in Regenerative Medicine
title Nonhuman Primate Induced Pluripotent Stem Cells in Regenerative Medicine
title_full Nonhuman Primate Induced Pluripotent Stem Cells in Regenerative Medicine
title_fullStr Nonhuman Primate Induced Pluripotent Stem Cells in Regenerative Medicine
title_full_unstemmed Nonhuman Primate Induced Pluripotent Stem Cells in Regenerative Medicine
title_short Nonhuman Primate Induced Pluripotent Stem Cells in Regenerative Medicine
title_sort nonhuman primate induced pluripotent stem cells in regenerative medicine
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345260/
https://www.ncbi.nlm.nih.gov/pubmed/22577396
http://dx.doi.org/10.1155/2012/767195
work_keys_str_mv AT wuyuehong nonhumanprimateinducedpluripotentstemcellsinregenerativemedicine
AT mishraanuja nonhumanprimateinducedpluripotentstemcellsinregenerativemedicine
AT qiuzhifang nonhumanprimateinducedpluripotentstemcellsinregenerativemedicine
AT farnsworthsteven nonhumanprimateinducedpluripotentstemcellsinregenerativemedicine
AT tardifsuzetted nonhumanprimateinducedpluripotentstemcellsinregenerativemedicine
AT hornsbypeterj nonhumanprimateinducedpluripotentstemcellsinregenerativemedicine

Ejemplares similares