Cargando…

Thy1-hAPP(Lond/Swe+) mouse model of Alzheimer's disease displays broad behavioral deficits in sensorimotor, cognitive and social function

Alzheimer's disease (AD), the most common form of dementia, is an age-dependent progressive neurodegenerative disorder. β-amyloid, a metabolic product of the amyloid precursor protein (APP), plays an important role in the pathogenesis of AD. The Thy1-hAPP(Lond/Swe+) (line 41) transgenic mouse o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Faizi, Mehrdad, Bader, Patrick L, Saw, Nay, Nguyen, Thuy-Vi V, Beraki, Simret, Wyss-Coray, Tony, Longo, Frank M, Shamloo, Mehrdad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Inc 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345358/ https://www.ncbi.nlm.nih.gov/pubmed/22574282 http://dx.doi.org/10.1002/brb3.41

Ejemplares similares

Npas4: A Neuronal Transcription Factor with a Key Role in Social and Cognitive Functions Relevant to Developmental Disorders
por: Coutellier, Laurence, et al.
Publicado: (2012)

A Pharmacological Screening Approach for Discovery of Neuroprotective Compounds in Ischemic Stroke
por: Beraki, Simret, et al.
Publicado: (2013)

Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease
por: Joshi, Amit U., et al.
Publicado: (2017)

Activity-dependent modulation of hippocampal synaptic plasticity via PirB and endocannabinoids
por: Djurisic, Maja, et al.
Publicado: (2018)

Role of Endoplasmic Reticulum Stress in Learning and Memory Impairment and Alzheimer's Disease-Like Neuropathology in the PS19 and APP(Swe) Mouse Models of Tauopathy and Amyloidosis
por: Briggs, Denise Isabelle, et al.
Publicado: (2017)

The HAPPE plus Event-Related (HAPPE+ER) software: A standardized preprocessing pipeline for event-related potential analyses
por: Monachino, A.D., et al.
Publicado: (2022)

Fazio Londe syndrome: A treatable disorder
por: Varadarajan, Poovazhagi, et al.
Publicado: (2015)

Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis
por: Joshi, Amit U, et al.
Publicado: (2018)

Dr Vaithianathan Satkunanayagam MBBS (Cey), DPM (Lond), FRCPsych (UK)
por: Nikapota, Anula
Publicado: (2014)

Potential biomarkers to follow the progression and treatment response of Huntington’s disease
por: Disatnik, Marie-Hélène, et al.
Publicado: (2016)

Neural compensation in presymptomatic hAPP mouse models of Alzheimer's disease
por: Ammassari-Teule, Martine
Publicado: (2020)

Edward Markham Skerritt, M.D. Lond., F.R.C.P.
Publicado: (1907)

Professor Narendra Nath Wig MD FRCPsych DPM.(Lond) 1930-2018
por: Gaind, Raghunandan
Publicado: (2019)

HAPPE: A Tool for Population Haplotype Analysis and Visualization in Editable Excel Tables
por: Feng, Cong, et al.
Publicado: (2022)

Reliability of the DSS-Swe Questionnaire
por: Jans, Anders, et al.
Publicado: (2023)

John Ewens, L.R.C.P. Lond., L.R.C.S. Edin.
Publicado: (1916)

Early onset of Fazio-Londe syndrome: the first case report from the Arabian Peninsula
por: Hossain, Mohammad Arif, et al.
Publicado: (2017)

Enantiomers of 2-methylglutamate and 2-methylglutamine selectively impact mouse brain metabolism and behavior
por: Wawro, Adam M., et al.
Publicado: (2021)

Transgenic Animals in Pharmaceutical and Biological Research in Iran
por: Faizi, Mehrdad
Publicado: (2013)

James Alexander Lindsay, M.A., M.D., F.R.C.P.(LOND.)
Publicado: (1932)

A neural circuit model for human sensorimotor timing
por: Egger, Seth W., et al.
Publicado: (2020)

Phytate Intake, Health and Disease: “Let Thy Food Be Thy Medicine and Medicine Be Thy Food”
por: Pujol, Antelm, et al.
Publicado: (2023)

Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice
por: Steffen, Johannes, et al.
Publicado: (2017)

Hypertension and Pathogenic hAPP Independently Induce White Matter Astrocytosis and Cognitive Impairment in the Rat
por: Levit, Alexander, et al.
Publicado: (2020)

Gaze patterns and brain activations in humans and marmosets in the Frith-Happé theory-of-mind animation task
por: Dureux, Audrey, et al.
Publicado: (2023)

Let food be thy medicine and medicine be thy food?
por: Stauss, Madelena, et al.
Publicado: (2018)

William Henry Stevens, M.R.C.S., L.R.C.P. Lond., L.S.A.
Publicado: (1913)

Internal models of sensorimotor integration regulate cortical dynamics
por: Egger, Seth W., et al.
Publicado: (2019)

Validation of the Swedish Trauma Registry (SweTrau)
por: Holmberg, Lina, et al.
Publicado: (2023)

The Harvard Automated Processing Pipeline for Electroencephalography (HAPPE): Standardized Processing Software for Developmental and High-Artifact Data
por: Gabard-Durnam, Laurel J., et al.
Publicado: (2018)

HAPPILEE: HAPPE In Low Electrode Electroencephalography, a standardized pre-processing software for lower density recordings
por: Lopez, K.L., et al.
Publicado: (2022)

Sensorimotor feedback loops are selectively sensitive to reward
por: Codol, Olivier, et al.
Publicado: (2023)

The Brown-Vialetto-Van Laere and Fazio Londe syndrome revisited: natural history, genetics, treatment and future perspectives
por: Bosch, Annet M, et al.
Publicado: (2012)

SweC and SweD are essential co-factors of the FtsEX-CwlO cell wall hydrolase complex in Bacillus subtilis
por: Brunet, Yannick R., et al.
Publicado: (2019)

Serum Corticosterone and Insulin Resistance as Early Biomarkers in the hAPP23 Overexpressing Mouse Model of Alzheimer’s Disease
por: Hendrickx, Jhana O., et al.
Publicado: (2021)

Goal-Directed Action Is Initially Impaired in a hAPP-J20 Mouse Model of Alzheimer’s Disease
por: Dhungana, Amolika, et al.
Publicado: (2023)

Variation in Group Composition Alters an Early-Stage Social Phenotype in hAPP-Transgenic J20 Mice
por: Lanooij, Suzanne D., et al.
Publicado: (2023)

Thy-1+ and Thy-1- natural killer cells. Only Thy-1- natural killer cells suppress dendritic cells
Publicado: (1986)

Cdk1 and SUMO Regulate Swe1 Stability
por: Simpson-Lavy, Kobi J., et al.
Publicado: (2010)

Cohort profile: the Swedish Pancreatitis Cohort (SwePan)
por: Selin, Daniel, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4ngq94lcelvong4d41enstftdj