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Human Origin for Livestock-Associated Methicillin-Resistant Staphylococcus aureus

Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of human morbidity and mortality worldwide. The emergence in the last decade of a livestock-associated MRSA (LA-MRSA) clone which also has the capacity to cause zoonotic infections in humans has raised important questions regarding...

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Detalles Bibliográficos
Autor principal: Fitzgerald, J. Ross
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345579/
https://www.ncbi.nlm.nih.gov/pubmed/22511352
http://dx.doi.org/10.1128/mBio.00082-12
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author Fitzgerald, J. Ross
author_facet Fitzgerald, J. Ross
author_sort Fitzgerald, J. Ross
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description Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of human morbidity and mortality worldwide. The emergence in the last decade of a livestock-associated MRSA (LA-MRSA) clone which also has the capacity to cause zoonotic infections in humans has raised important questions regarding its origin and its potential to cause human epidemics. An important study by L. B. Price et al. [mBio 3(1):e00305-11, 2012] provides evidence for a human ancestral origin for LA-MRSA, raising concerns about agricultural practices that may have contributed to its emergence and expansion. The study highlights the potential for comparative whole-genome sequencing of closely related strains to provide valuable insights into the evolutionary history of bacterial pathogens.
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spelling pubmed-33455792012-05-09 Human Origin for Livestock-Associated Methicillin-Resistant Staphylococcus aureus Fitzgerald, J. Ross mBio Commentary Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of human morbidity and mortality worldwide. The emergence in the last decade of a livestock-associated MRSA (LA-MRSA) clone which also has the capacity to cause zoonotic infections in humans has raised important questions regarding its origin and its potential to cause human epidemics. An important study by L. B. Price et al. [mBio 3(1):e00305-11, 2012] provides evidence for a human ancestral origin for LA-MRSA, raising concerns about agricultural practices that may have contributed to its emergence and expansion. The study highlights the potential for comparative whole-genome sequencing of closely related strains to provide valuable insights into the evolutionary history of bacterial pathogens. American Society of Microbiology 2012-04-17 /pmc/articles/PMC3345579/ /pubmed/22511352 http://dx.doi.org/10.1128/mBio.00082-12 Text en Copyright © 2012 Fitzgerald http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License (http://creativecommons.org/licenses/by-nc-sa/3.0/) , which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Commentary
Fitzgerald, J. Ross
Human Origin for Livestock-Associated Methicillin-Resistant Staphylococcus aureus
title Human Origin for Livestock-Associated Methicillin-Resistant Staphylococcus aureus
title_full Human Origin for Livestock-Associated Methicillin-Resistant Staphylococcus aureus
title_fullStr Human Origin for Livestock-Associated Methicillin-Resistant Staphylococcus aureus
title_full_unstemmed Human Origin for Livestock-Associated Methicillin-Resistant Staphylococcus aureus
title_short Human Origin for Livestock-Associated Methicillin-Resistant Staphylococcus aureus
title_sort human origin for livestock-associated methicillin-resistant staphylococcus aureus
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345579/
https://www.ncbi.nlm.nih.gov/pubmed/22511352
http://dx.doi.org/10.1128/mBio.00082-12
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