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LIPOPREDICT: Bacterial lipoprotein prediction server
Bacterial lipoproteins have many important functions owing to their essential nature and roles in pathogenesis and represent a class of possible vaccine candidates. The prediction of bacterial lipoproteins from sequence is thus an important task for computational vaccinology. A Support Vector Machin...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346017/ https://www.ncbi.nlm.nih.gov/pubmed/22570522 http://dx.doi.org/10.6026/97320630008394 |
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author | Kumari, S Ramya Kadam, Kiran Badwaik, Ritesh Jayaraman, Valadi K |
author_facet | Kumari, S Ramya Kadam, Kiran Badwaik, Ritesh Jayaraman, Valadi K |
author_sort | Kumari, S Ramya |
collection | PubMed |
description | Bacterial lipoproteins have many important functions owing to their essential nature and roles in pathogenesis and represent a class of possible vaccine candidates. The prediction of bacterial lipoproteins from sequence is thus an important task for computational vaccinology. A Support Vector Machines (SVM) based module for predicting bacterial lipoproteins, LIPOPREDICT, has been developed. The best performing sequence model were generated using selected dipeptide composition, which gave 97% accuracy of prediction. The results obtained were compared very well with those of previously developed methods. AVAILABILITY: The database is available for free at www.lipopredict.cdac.in |
format | Online Article Text |
id | pubmed-3346017 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Biomedical Informatics |
record_format | MEDLINE/PubMed |
spelling | pubmed-33460172012-05-08 LIPOPREDICT: Bacterial lipoprotein prediction server Kumari, S Ramya Kadam, Kiran Badwaik, Ritesh Jayaraman, Valadi K Bioinformation Server Bacterial lipoproteins have many important functions owing to their essential nature and roles in pathogenesis and represent a class of possible vaccine candidates. The prediction of bacterial lipoproteins from sequence is thus an important task for computational vaccinology. A Support Vector Machines (SVM) based module for predicting bacterial lipoproteins, LIPOPREDICT, has been developed. The best performing sequence model were generated using selected dipeptide composition, which gave 97% accuracy of prediction. The results obtained were compared very well with those of previously developed methods. AVAILABILITY: The database is available for free at www.lipopredict.cdac.in Biomedical Informatics 2012-04-30 /pmc/articles/PMC3346017/ /pubmed/22570522 http://dx.doi.org/10.6026/97320630008394 Text en © 2012 Biomedical Informatics This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited. |
spellingShingle | Server Kumari, S Ramya Kadam, Kiran Badwaik, Ritesh Jayaraman, Valadi K LIPOPREDICT: Bacterial lipoprotein prediction server |
title | LIPOPREDICT: Bacterial lipoprotein prediction server |
title_full | LIPOPREDICT: Bacterial lipoprotein prediction server |
title_fullStr | LIPOPREDICT: Bacterial lipoprotein prediction server |
title_full_unstemmed | LIPOPREDICT: Bacterial lipoprotein prediction server |
title_short | LIPOPREDICT: Bacterial lipoprotein prediction server |
title_sort | lipopredict: bacterial lipoprotein prediction server |
topic | Server |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346017/ https://www.ncbi.nlm.nih.gov/pubmed/22570522 http://dx.doi.org/10.6026/97320630008394 |
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