Cargando…

Six-transmembrane Topology for Golgi Anti-apoptotic Protein (GAAP) and Bax Inhibitor 1 (BI-1) Provides Model for the Transmembrane Bax Inhibitor-containing Motif (TMBIM) Family

The Golgi anti-apoptotic protein (GAAP) is a hydrophobic Golgi protein that regulates intracellular calcium fluxes and apoptosis. GAAP is highly conserved throughout eukaryotes and some strains of vaccinia virus (VACV) and camelpox virus. Based on sequence, phylogeny, and hydrophobicity, GAAPs were...

Descripción completa

Detalles Bibliográficos
Autores principales:	Carrara, Guia, Saraiva, Nuno, Gubser, Caroline, Johnson, Benjamin F., Smith, Geoffrey L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2012
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346125/ https://www.ncbi.nlm.nih.gov/pubmed/22418439 http://dx.doi.org/10.1074/jbc.M111.336149

Ejemplares similares

TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy through regulation of lysosomal calcium
por: Kim, Hyun-Kyoung, et al.
Publicado: (2020)

TMP21 Transmembrane Domain Regulates γ-Secretase Cleavage
por: Pardossi-Piquard, Raphaëlle, et al.
Publicado: (2009)

Control of Periplasmic Interdomain Thiol:Disulfide Exchange in the Transmembrane Oxidoreductase DsbD
por: Mavridou, Despoina A. I., et al.
Publicado: (2009)

APH1 Polar Transmembrane Residues Regulate the Assembly and Activity of Presenilin Complexes
por: Pardossi-Piquard, Raphaëlle, et al.
Publicado: (2009)

The Evolutionary Conserved Transmembrane BAX Inhibitor Motif (TMBIM) Containing Protein Family Members 5 and 6 Are Essential for the Development and Survival of Drosophila melanogaster
por: Zhang, Li, et al.
Publicado: (2021)

The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR): THREE-DIMENSIONAL STRUCTURE AND LOCALIZATION OF A CHANNEL GATE
por: Rosenberg, Mark F., et al.
Publicado: (2011)

Mechanical transduction of cytoplasmic-to-transmembrane-domain movements in a hyperpolarization-activated cyclic nucleotide–gated cation channel
por: Gross, Christine, et al.
Publicado: (2018)

Cryo-electron microscopy structure and potential enzymatic function of human six-transmembrane epithelial antigen of the prostate 1 (STEAP1)
por: Oosterheert, Wout, et al.
Publicado: (2020)

Stimulation of cell invasion by the Golgi Ion Channel GAAP/TMBIM4 via an H(2)O(2)-Dependent Mechanism
por: Almeida, Nuno, et al.
Publicado: (2019)

Transmembrane BAX Inhibitor-1 Motif Containing Protein 5 (TMBIM5) Sustains Mitochondrial Structure, Shape, and Function by Impacting the Mitochondrial Protein Synthesis Machinery
por: Seitaj, Bruno, et al.
Publicado: (2020)

Gating control of the cardiac sodium channel Nav1.5 by its β3-subunit involves distinct roles for a transmembrane glutamic acid and the extracellular domain
por: Salvage, Samantha C., et al.
Publicado: (2019)

Structure of a Conserved Golgi Complex-targeting Signal in Coronavirus Envelope Proteins
por: Li, Yan, et al.
Publicado: (2014)

Human and Viral Golgi Anti-apoptotic Proteins (GAAPs) Oligomerize via Different Mechanisms and Monomeric GAAP Inhibits Apoptosis and Modulates Calcium
por: Saraiva, Nuno, et al.
Publicado: (2013)

Solution NMR Structure of the Ca(2+)-bound N-terminal Domain of CaBP7: A REGULATOR OF GOLGI TRAFFICKING
por: McCue, Hannah V., et al.
Publicado: (2012)

Molecular Recognition of Chymotrypsin by the Serine Protease Inhibitor Ecotin from Yersinia pestis
por: Clark, Elizabeth A., et al.
Publicado: (2011)

In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1
por: Christensen, Emily M., et al.
Publicado: (2021)

A Novel Cofactor-binding Mode in Bacterial IMP Dehydrogenases Explains Inhibitor Selectivity
por: Makowska-Grzyska, Magdalena, et al.
Publicado: (2015)

Mutations in the Carboxyl-terminal SEC24 Binding Motif of the Serotonin Transporter Impair Folding of the Transporter
por: El-Kasaby, Ali, et al.
Publicado: (2010)

The Three-dimensional Structure of Carnocyclin A Reveals That Many Circular Bacteriocins Share a Common Structural Motif
por: Martin-Visscher, Leah A., et al.
Publicado: (2009)

Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR
por: Owen, C. David, et al.
Publicado: (2015)

Mechanism of Histone H3K4me3 Recognition by the Plant Homeodomain of Inhibitor of Growth 3
por: Kim, Sophia, et al.
Publicado: (2016)

Characterization of the Human Sigma-1 Receptor Chaperone Domain Structure and Binding Immunoglobulin Protein (BiP) Interactions
por: Ortega-Roldan, Jose Luis, et al.
Publicado: (2013)

ACE2 X-Ray Structures Reveal a Large Hinge-bending Motion Important for Inhibitor Binding and Catalysis
por: Towler, Paul, et al.
Publicado: (2004)

The Truncated C-terminal RNA Recognition Motif of TDP-43 Protein Plays a Key Role in Forming Proteinaceous Aggregates
por: Wang, Yi-Ting, et al.
Publicado: (2013)

Accessory Interaction Motifs in the Atg19 Cargo Receptor Enable Strong Binding to the Clustered Ubiquitin-related Atg8 Protein
por: Abert, Christine, et al.
Publicado: (2016)

Crystal Structures of Human Choline Kinase Isoforms in Complex with Hemicholinium-3: SINGLE AMINO ACID NEAR THE ACTIVE SITE INFLUENCES INHIBITOR SENSITIVITY
por: Hong, Bum Soo, et al.
Publicado: (2010)

The N Domain of Human Angiotensin-I-converting Enzyme: THE ROLE OF N-GLYCOSYLATION AND THE CRYSTAL STRUCTURE IN COMPLEX WITH AN N DOMAIN-SPECIFIC PHOSPHINIC INHIBITOR, RXP407
por: Anthony, Colin S., et al.
Publicado: (2010)

Albumin-conjugated C34 Peptide HIV-1 Fusion Inhibitor: EQUIPOTENT TO C34 AND T-20 IN VITRO WITH SUSTAINED ACTIVITY IN SCID-HU THY/LIV MICE
por: Stoddart, Cheryl A., et al.
Publicado: (2008)

Mapping the IκB Kinase β (IKKβ)-binding Interface of the B14 Protein, a Vaccinia Virus Inhibitor of IKKβ-mediated Activation of Nuclear Factor κB
por: Benfield, Camilla T. O., et al.
Publicado: (2011)

Dissection Study on the Severe Acute Respiratory Syndrome 3C-like Protease Reveals the Critical Role of the Extra Domain in Dimerization of the Enzyme: DEFINING THE EXTRA DOMAIN AS A NEW TARGET FOR DESIGN OF HIGHLY SPECIFIC PROTEASE INHIBITORS
por: Shi, Jiahai, et al.
Publicado: (2004)

Transmembrane BAX inhibitor motif containing 6 suppresses presenilin-2 to preserve mitochondrial integrity after myocardial ischemia-reperfusion injury
por: Ma, Li, et al.
Publicado: (2023)

The Transmembrane Oligomers of Coronavirus Protein E
por: Torres, Jaume, et al.
Publicado: (2005)

Structure of the N-terminal Region of Complement Factor H and Conformational Implications of Disease-linked Sequence Variations
por: Hocking, Henry G., et al.
Publicado: (2008)

Crystal Structure of a Functional Dimer of the PhoQ Sensor Domain
por: Cheung, Jonah, et al.
Publicado: (2008)

Function and Structure of a Prokaryotic Formylglycine-generating Enzyme
por: Carlson, Brian L., et al.
Publicado: (2008)

Prion Protein Complexed to N2a Cellular RNAs through Its N-terminal Domain Forms Aggregates and Is Toxic to Murine Neuroblastoma Cells
por: Gomes, Mariana P. B., et al.
Publicado: (2008)

Intra- and Intermonomer Interactions Are Required to Synergistically Facilitate ATP Hydrolysis in Hsp90
por: Cunningham, Christian N., et al.
Publicado: (2008)

A Common Theme in Interaction of Bacterial Immunoglobulin-binding Proteins with Immunoglobulins Illustrated in the Equine System
por: Lewis, Melanie J., et al.
Publicado: (2008)

A Common β-Sheet Architecture Underlies in Vitro and in Vivo β(2)-Microglobulin Amyloid Fibrils
por: Jahn, Thomas R., et al.
Publicado: (2008)

Appearance and Propagation of Polyglutamine-based Amyloids in Yeast: TYROSINE RESIDUES ENABLE POLYMER FRAGMENTATION
por: Alexandrov, Ilya M., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_tvc0kb5bpfhon875ffrv6ajcgn