Cargando…

Importance of Human Leukocyte Antigen (HLA) Class I and II Alleles on the Risk of Multiple Sclerosis

Multiple sclerosis (MS) is a complex disease of the central nervous system of unknown etiology. The human leukocyte antigen (HLA) locus on chromosome 6 confers a considerable part of the susceptibility to MS, and the most important factor is the class II allele HLA-DRB1*15:01. In addition, we and ot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Link, Jenny, Kockum, Ingrid, Lorentzen, Åslaug R., Lie, Benedicte A., Celius, Elisabeth G., Westerlind, Helga, Schaffer, Marie, Alfredsson, Lars, Olsson, Tomas, Brynedal, Boel, Harbo, Hanne F., Hillert, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346735/ https://www.ncbi.nlm.nih.gov/pubmed/22586495 http://dx.doi.org/10.1371/journal.pone.0036779

Ejemplares similares

Identity-by-descent mapping in a Scandinavian multiple sclerosis cohort
por: Westerlind, Helga, et al.
Publicado: (2015)

Human Leukocyte Antigen Genes and Interferon Beta Preparations Influence Risk of Developing Neutralizing Anti-Drug Antibodies in Multiple Sclerosis
por: Link, Jenny, et al.
Publicado: (2014)

Oligoclonal Band Status in Scandinavian Multiple Sclerosis Patients Is Associated with Specific Genetic Risk Alleles
por: Mero, Inger-Lise, et al.
Publicado: (2013)

Different HLA-DRB1 allele distributions in distinct clinical subgroups of sarcoidosis patients
por: Grunewald, Johan, et al.
Publicado: (2010)

Systematic approach demonstrates enrichment of multiple interactions between non-HLA risk variants and HLA-DRB1 risk alleles in rheumatoid arthritis
por: Diaz-Gallo, Lina-Marcela, et al.
Publicado: (2018)

HLA-A Confers an HLA-DRB1 Independent Influence on the Risk of Multiple Sclerosis
por: Brynedal, Boel, et al.
Publicado: (2007)

The familial risk and heritability of multiple sclerosis and its onset phenotypes: A case–control study
por: Boles, Graysen Steele, et al.
Publicado: (2023)

Understanding interactions between risk factors, and assessing the utility of the additive and multiplicative models through simulations
por: Diaz-Gallo, Lina-Marcela, et al.
Publicado: (2021)

Organic solvents and MS susceptibility: Interaction with MS risk HLA genes
por: Hedström, Anna Karin, et al.
Publicado: (2018)

The interaction between smoking and HLA genes in multiple sclerosis: replication and refinement
por: Hedström, Anna Karin, et al.
Publicado: (2017)

Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype
por: Terao, Chikashi, et al.
Publicado: (2019)

Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype
por: Terao, Chikashi, et al.
Publicado: (2019)

Low fish consumption is associated with a small increased risk of MS
por: Hedström, Anna Karin, et al.
Publicado: (2020)

Low sun exposure increases multiple sclerosis risk both directly and indirectly
por: Hedström, Anna Karin, et al.
Publicado: (2019)

Late Onset Myasthenia Gravis Is Associated with HLA DRB1*15:01 in the Norwegian Population
por: Maniaol, Angelina H., et al.
Publicado: (2012)

Stressful life events are associated with the risk of multiple sclerosis
por: Jiang, X., et al.
Publicado: (2020)

Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis
por: Hedström, Anna Karin, et al.
Publicado: (2014)

Familial risk of early- and late-onset multiple sclerosis: a Swedish nationwide study
por: Song, Jie, et al.
Publicado: (2018)

Confounding effect of blood volume and body mass index on blood neurofilament light chain levels
por: Manouchehrinia, Ali, et al.
Publicado: (2020)

Smoking Attributable Risk in Multiple Sclerosis
por: Manouchehrinia, Ali, et al.
Publicado: (2022)

Interaction between passive smoking and two HLA genes with regard to multiple sclerosis risk
por: Hedström, Anna Karin, et al.
Publicado: (2014)

Spasticity treatment patterns among people with multiple sclerosis: a Swedish cohort study
por: Smith, Kelsi A, et al.
Publicado: (2023)

Association between exposure to combustion-related air pollution and multiple sclerosis risk
por: Hedström, Anna Karin, et al.
Publicado: (2023)

Allele-Independent Turnover of Human Leukocyte Antigen (HLA) Class Ia Molecules
por: Prevosto, Claudia, et al.
Publicado: (2016)

Smoking and Epstein–Barr virus infection in multiple sclerosis development
por: Hedström, Anna Karin, et al.
Publicado: (2020)

DRB1–environment interactions in multiple sclerosis etiology: results from two Swedish case–control studies
por: Hedström, Anna Karin, et al.
Publicado: (2021)

Season of birth is associated with multiple sclerosis and disease severity
por: Stridh, P, et al.
Publicado: (2021)

A genomic study on distribution of human leukocyte antigen (HLA)-A and HLA-B alleles in Lak population of Iran()
por: Shahsavar, Farhad, et al.
Publicado: (2016)

High Levels of Epstein–Barr Virus Nuclear Antigen-1-Specific Antibodies and Infectious Mononucleosis Act Both Independently and Synergistically to Increase Multiple Sclerosis Risk
por: Hedström, Anna Karin, et al.
Publicado: (2020)

Melanoma and Human Leukocyte Antigen (HLA): Immunogenicity of 69 HLA Class I Alleles With 11 Antigens Expressed in Melanoma Tumors
por: Georgopoulos, Apostolos P, et al.
Publicado: (2023)

Unmet Needs in Rheumatoid Arthritis: A Subgroup of Patients With High Levels of Pain, Fatigue, and Psychosocial Distress 3 Years After Diagnosis
por: Lindqvist, Joakim, et al.
Publicado: (2022)

Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling
por: Lundtoft, Christian, et al.
Publicado: (2020)

Alcohol Consumption and Risk of Common Autoimmune Inflammatory Diseases—Evidence From a Large-Scale Genetic Analysis Totaling 1 Million Individuals
por: Jiang, Xia, et al.
Publicado: (2021)

Interaction Analysis between HLA-DRB1 Shared Epitope Alleles and MHC Class II Transactivator CIITA Gene with Regard to Risk of Rheumatoid Arthritis
por: Ronninger, Marcus, et al.
Publicado: (2012)

JC Polyomavirus Infection Is Strongly Controlled by Human Leucocyte Antigen Class II Variants
por: Sundqvist, Emilie, et al.
Publicado: (2014)

Siblings of patients with rheumatoid arthritis have an increased mortality rate: a Swedish cohort study
por: Westerlind, Helga, et al.
Publicado: (2020)

The DQB1(*)03:02 Genotype and Treatment for Pain in People With and Without Multiple Sclerosis
por: Burkill, Sarah, et al.
Publicado: (2020)

Multiple Sclerosis Risk Allele in CLEC16A Acts as an Expression Quantitative Trait Locus for CLEC16A and SOCS1 in CD4+ T Cells
por: Leikfoss, Ingvild S., et al.
Publicado: (2015)

Mendelian randomization shows a causal effect of low vitamin D on multiple sclerosis risk
por: Rhead, Brooke, et al.
Publicado: (2016)

Frequency of null allele of Human Leukocyte Antigen-G (HLA-G) locus in subjects to recurrent miscarriage
por: Alizadeh, Nazila, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_leprbuer2nhocgh3biaucjgd58