Overfeeding Reduces Insulin Sensitivity and Increases Oxidative Stress, without Altering Markers of Mitochondrial Content and Function in Humans

BACKGROUND: Mitochondrial dysfunction and increased oxidative stress are associated with obesity and type 2 diabetes. High fat feeding induces insulin resistance and increases skeletal muscle oxidative stress in rodents, but there is controversy as to whether skeletal muscle mitochondrial biogenesis...

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Detalles Bibliográficos
Autores principales: Samocha-Bonet, Dorit, Campbell, Lesley V., Mori, Trevor A., Croft, Kevin D., Greenfield, Jerry R., Turner, Nigel, Heilbronn, Leonie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346759/
https://www.ncbi.nlm.nih.gov/pubmed/22586466
http://dx.doi.org/10.1371/journal.pone.0036320

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