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Computational Modeling and Numerical Methods for Spatiotemporal Calcium Cycling in Ventricular Myocytes

Intracellular calcium (Ca) cycling dynamics in cardiac myocytes is regulated by a complex network of spatially distributed organelles, such as sarcoplasmic reticulum (SR), mitochondria, and myofibrils. In this study, we present a mathematical model of intracellular Ca cycling and numerical and compu...

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Detalles Bibliográficos
Autores principales: Nivala, Michael, de Lange, Enno, Rovetti, Robert, Qu, Zhilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346978/
https://www.ncbi.nlm.nih.gov/pubmed/22586402
http://dx.doi.org/10.3389/fphys.2012.00114