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A Pleiotropic Role for the Orphan Nuclear Receptor Small Heterodimer Partner in Lipid Homeostasis and Metabolic Pathways

Nuclear receptors (NRs) comprise one of the most abundant classes of transcriptional regulators of metabolic diseases and have emerged as promising pharmaceutical targets. Small heterodimer partner (SHP; NR0B2) is a unique orphan NR lacking a DNA-binding domain but contains a putative ligand-binding...

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Detalles Bibliográficos
Autores principales:	Garruti, Gabriella, Wang, Helen H., Bonfrate, Leonilde, de Bari, Ornella, Wang, David Q.-H., Portincasa, Piero
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346990/ https://www.ncbi.nlm.nih.gov/pubmed/22577560 http://dx.doi.org/10.1155/2012/304292

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