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Food Supplement 20070721-GX May Increase CD34(+) Stem Cells and Telomerase Activity
Few rejuvenation and antiaging markers are used to evaluate food supplements. We measured three markers in peripheral blood to evaluate the antiaging effects of a food supplement containing placental extract. Samples were evaluated for CD34(+) cells, insulin-like growth factor 1 (IGF1), and telomera...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346997/ https://www.ncbi.nlm.nih.gov/pubmed/22577293 http://dx.doi.org/10.1155/2012/498051 |
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author | Lin, Po-Cheng Chiou, Tzyy-Wen Liu, Po-Yen Chen, Shee-Ping Wang, Hsin-I Huang, Pi-Chun Lin, Shinn-Zong Harn, Horng-Jyh |
author_facet | Lin, Po-Cheng Chiou, Tzyy-Wen Liu, Po-Yen Chen, Shee-Ping Wang, Hsin-I Huang, Pi-Chun Lin, Shinn-Zong Harn, Horng-Jyh |
author_sort | Lin, Po-Cheng |
collection | PubMed |
description | Few rejuvenation and antiaging markers are used to evaluate food supplements. We measured three markers in peripheral blood to evaluate the antiaging effects of a food supplement containing placental extract. Samples were evaluated for CD34(+) cells, insulin-like growth factor 1 (IGF1), and telomerase activity, which are all markers related to aging. To control the quality of this food supplement, five active components were monitored. In total, we examined 44 individuals who took the food supplement from 1.2 months to 23 months; the average number of CD34(+) cells was almost 6-fold higher in the experimental group compared with the control group. Food supplement intake did not change serum IGF1 levels significantly. Finally, the average telomerase activity was 30% higher in the subjects taking this food supplement. In summary, our results suggest that the placental extract in the food supplement might contribute to rejuvenation and antiaging. |
format | Online Article Text |
id | pubmed-3346997 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-33469972012-05-10 Food Supplement 20070721-GX May Increase CD34(+) Stem Cells and Telomerase Activity Lin, Po-Cheng Chiou, Tzyy-Wen Liu, Po-Yen Chen, Shee-Ping Wang, Hsin-I Huang, Pi-Chun Lin, Shinn-Zong Harn, Horng-Jyh J Biomed Biotechnol Research Article Few rejuvenation and antiaging markers are used to evaluate food supplements. We measured three markers in peripheral blood to evaluate the antiaging effects of a food supplement containing placental extract. Samples were evaluated for CD34(+) cells, insulin-like growth factor 1 (IGF1), and telomerase activity, which are all markers related to aging. To control the quality of this food supplement, five active components were monitored. In total, we examined 44 individuals who took the food supplement from 1.2 months to 23 months; the average number of CD34(+) cells was almost 6-fold higher in the experimental group compared with the control group. Food supplement intake did not change serum IGF1 levels significantly. Finally, the average telomerase activity was 30% higher in the subjects taking this food supplement. In summary, our results suggest that the placental extract in the food supplement might contribute to rejuvenation and antiaging. Hindawi Publishing Corporation 2012 2012-04-22 /pmc/articles/PMC3346997/ /pubmed/22577293 http://dx.doi.org/10.1155/2012/498051 Text en Copyright © 2012 Po-Cheng Lin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Lin, Po-Cheng Chiou, Tzyy-Wen Liu, Po-Yen Chen, Shee-Ping Wang, Hsin-I Huang, Pi-Chun Lin, Shinn-Zong Harn, Horng-Jyh Food Supplement 20070721-GX May Increase CD34(+) Stem Cells and Telomerase Activity |
title | Food Supplement 20070721-GX May Increase CD34(+) Stem Cells and Telomerase Activity |
title_full | Food Supplement 20070721-GX May Increase CD34(+) Stem Cells and Telomerase Activity |
title_fullStr | Food Supplement 20070721-GX May Increase CD34(+) Stem Cells and Telomerase Activity |
title_full_unstemmed | Food Supplement 20070721-GX May Increase CD34(+) Stem Cells and Telomerase Activity |
title_short | Food Supplement 20070721-GX May Increase CD34(+) Stem Cells and Telomerase Activity |
title_sort | food supplement 20070721-gx may increase cd34(+) stem cells and telomerase activity |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346997/ https://www.ncbi.nlm.nih.gov/pubmed/22577293 http://dx.doi.org/10.1155/2012/498051 |
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