The Coronavirus E Protein: Assembly and Beyond

The coronavirus E protein is a small membrane protein that has an important role in the assembly of virions. Recent studies have indicated that the E protein has functions during infection beyond assembly, including in virus egress and in the host stress response. Additionally, the E protein has ion...

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Detalles Bibliográficos
Autores principales: Ruch, Travis R., Machamer, Carolyn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347032/
https://www.ncbi.nlm.nih.gov/pubmed/22590676
http://dx.doi.org/10.3390/v4030363
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author Ruch, Travis R.
Machamer, Carolyn E.
author_facet Ruch, Travis R.
Machamer, Carolyn E.
author_sort Ruch, Travis R.
collection PubMed
description The coronavirus E protein is a small membrane protein that has an important role in the assembly of virions. Recent studies have indicated that the E protein has functions during infection beyond assembly, including in virus egress and in the host stress response. Additionally, the E protein has ion channel activity, interacts with host proteins, and may have multiple membrane topologies. The goal of this review is to highlight the properties and functions of the E protein, and speculate on how they may be related.
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spelling pubmed-33470322012-05-15 The Coronavirus E Protein: Assembly and Beyond Ruch, Travis R. Machamer, Carolyn E. Viruses Review The coronavirus E protein is a small membrane protein that has an important role in the assembly of virions. Recent studies have indicated that the E protein has functions during infection beyond assembly, including in virus egress and in the host stress response. Additionally, the E protein has ion channel activity, interacts with host proteins, and may have multiple membrane topologies. The goal of this review is to highlight the properties and functions of the E protein, and speculate on how they may be related. MDPI 2012-03-08 /pmc/articles/PMC3347032/ /pubmed/22590676 http://dx.doi.org/10.3390/v4030363 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Ruch, Travis R.
Machamer, Carolyn E.
The Coronavirus E Protein: Assembly and Beyond
title The Coronavirus E Protein: Assembly and Beyond
title_full The Coronavirus E Protein: Assembly and Beyond
title_fullStr The Coronavirus E Protein: Assembly and Beyond
title_full_unstemmed The Coronavirus E Protein: Assembly and Beyond
title_short The Coronavirus E Protein: Assembly and Beyond
title_sort coronavirus e protein: assembly and beyond
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347032/
https://www.ncbi.nlm.nih.gov/pubmed/22590676
http://dx.doi.org/10.3390/v4030363
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