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Covalent Binding Antibodies Suppress Advanced Glycation: On the Innate Tier of Adaptive Immunity
Non-enzymatic protein glycation is a source of metabolic stress that contributes to cytotoxicity and tissue damage. Hyperglycemia has been linked to elevation of advanced glycation endproducts, which mediate much of the vascular pathology leading to diabetic complications. Enhanced glycation of immu...
Autores principales: | Shcheglova, T., Makker, S. P., Tramontano, A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
A.I. Gordeyev
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347515/ https://www.ncbi.nlm.nih.gov/pubmed/22649604 |
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