Chromatin Diminution Process Regulates rRNA Gene Copy Number in Freshwater Copepods

The results of quantitative PCR (qPCR) presented in the paper clearly demonstrate that the sixteen-fold genome reduction inCyclops kolensisduring chromatin diminution (from 15.3 pg to 0.98 pg) results in a dramatic decrease in ribosomal RNA gene copy numbers in the genome of a somatic cell line by m...

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Autores principales: Zagoskin, M. V., Marshak, T. L., Mukha, D. V., Grishanin, A. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347581/
https://www.ncbi.nlm.nih.gov/pubmed/22649664
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author Zagoskin, M. V.
Marshak, T. L.
Mukha, D. V.
Grishanin, A. K.
author_facet Zagoskin, M. V.
Marshak, T. L.
Mukha, D. V.
Grishanin, A. K.
author_sort Zagoskin, M. V.
collection PubMed
description The results of quantitative PCR (qPCR) presented in the paper clearly demonstrate that the sixteen-fold genome reduction inCyclops kolensisduring chromatin diminution (from 15.3 pg to 0.98 pg) results in a dramatic decrease in ribosomal RNA gene copy numbers in the genome of a somatic cell line by more than two orders of magnitude. The results presented allow for the consideration of the chromatin diminution as a mechanism of rDNA copy number regulation.
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spelling pubmed-33475812012-05-30 Chromatin Diminution Process Regulates rRNA Gene Copy Number in Freshwater Copepods Zagoskin, M. V. Marshak, T. L. Mukha, D. V. Grishanin, A. K. Acta Naturae Research Article The results of quantitative PCR (qPCR) presented in the paper clearly demonstrate that the sixteen-fold genome reduction inCyclops kolensisduring chromatin diminution (from 15.3 pg to 0.98 pg) results in a dramatic decrease in ribosomal RNA gene copy numbers in the genome of a somatic cell line by more than two orders of magnitude. The results presented allow for the consideration of the chromatin diminution as a mechanism of rDNA copy number regulation. A.I. Gordeyev 2010 /pmc/articles/PMC3347581/ /pubmed/22649664 Text en Copyright © 2010 Park-media Ltd. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zagoskin, M. V.
Marshak, T. L.
Mukha, D. V.
Grishanin, A. K.
Chromatin Diminution Process Regulates rRNA Gene Copy Number in Freshwater Copepods
title Chromatin Diminution Process Regulates rRNA Gene Copy Number in Freshwater Copepods
title_full Chromatin Diminution Process Regulates rRNA Gene Copy Number in Freshwater Copepods
title_fullStr Chromatin Diminution Process Regulates rRNA Gene Copy Number in Freshwater Copepods
title_full_unstemmed Chromatin Diminution Process Regulates rRNA Gene Copy Number in Freshwater Copepods
title_short Chromatin Diminution Process Regulates rRNA Gene Copy Number in Freshwater Copepods
title_sort chromatin diminution process regulates rrna gene copy number in freshwater copepods
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347581/
https://www.ncbi.nlm.nih.gov/pubmed/22649664
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AT mukhadv chromatindiminutionprocessregulatesrrnagenecopynumberinfreshwatercopepods
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