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The Role of p66shc in Oxidative Stress and Apoptosis

p66shcis a gene that regulates the level of reactive oxygen species (ROS), apoptosis induction, and lifespan in mammals. Miceknocked out forp66shchave a lifespan~30% longeranddemonstrate an enhanced resistance to oxidative stress and age-related pathologies such as hypercholesterolemia, ischemia, an...

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Detalles Bibliográficos
Autor principal:	Galimov, E.R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	A.I. Gordeyev 2010
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347587/ https://www.ncbi.nlm.nih.gov/pubmed/22649663

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