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Bacterial Synthesis and Purification of Normal and Mutant Forms of Human FGFR3 Transmembrane Segment
The fibroblast growth factor receptor 3 (FGFR3) is a protein belonging to the family of receptor tyrosine kinases. FGFR3 plays an important role in human skeletal development. Mutations in this protein, including Gly380Arg or Ala391Glu substitutions in the transmembrane (TM) region, can cause differ...
Autores principales: | Goncharuk, S.A., Goncharuk, M.V., Mayzel, M.L., Lesovoy, D.M., Chupin, V.V., Bocharov, E.V., Arseniev, A.S., Kirpichnikov, M.P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
A.I. Gordeyev
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347607/ https://www.ncbi.nlm.nih.gov/pubmed/22649697 |
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