Cargando…

Overexpression of eIF3a in Squamous Cell Carcinoma of the Oral Cavity and Its Putative Relation to Chemotherapy Response

The eukaryotic translation initiation factor eIF3a is one of the core subunits of the translation initiation complex eIF3, responsible for ribosomal subunit joining and mRNA recruitment to the ribosome. It is known to play an important role in general translation initiation as well as in the specifi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Spilka, Rita, Laimer, Klaus, Bachmann, Felix, Spizzo, Gilbert, Vogetseder, Alexander, Wieser, Manuel, Müller, Heimo, Haybaeck, Johannes, Obrist, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347757/ https://www.ncbi.nlm.nih.gov/pubmed/22619676 http://dx.doi.org/10.1155/2012/901956

Ejemplares similares

Dysregulation of Translation Factors EIF2S1, EIF5A and EIF6 in Intestinal-Type Adenocarcinoma (ITAC)
por: Schatz, Christoph, et al.
Publicado: (2021)

Correlation of COX-2 and Ep-CAM overexpression in human invasive breast cancer and its impact on survival
por: Spizzo, G, et al.
Publicado: (2003)

Overexpression of EIF5A2 Predicts Poor Prognosis in Patients with Oral Squamous Cell Carcinoma
por: Lin, Yueh-Min, et al.
Publicado: (2020)

The Role of mTOR and eIF Signaling in Benign Endometrial Diseases
por: Driva, Tatiana S., et al.
Publicado: (2022)

Inhibition of EIF2α Dephosphorylation Decreases Cell Viability and Synergizes with Standard-of-Care Chemotherapeutics in Head and Neck Squamous Cell Carcinoma
por: Cyran, Anna M., et al.
Publicado: (2023)

Stemness and chemotherapeutic drug resistance induced by EIF5A2 overexpression in esophageal squamous cell carcinoma
por: Yang, Hong, et al.
Publicado: (2015)

Soluble EpCAM levels in ascites correlate with positive cytology and neutralize catumaxomab activity in vitro
por: Seeber, Andreas, et al.
Publicado: (2015)

Synergistic activation of eIF4A by eIF4B and eIF4G
por: Nielsen, Klaus H., et al.
Publicado: (2011)

eIF4E Overexpression Is Associated with Poor Prognoses of Ovarian Cancer
por: Zheng, Jun, et al.
Publicado: (2020)

EpCAM overexpression prolongs proliferative capacity of primary human breast epithelial cells and supports hyperplastic growth
por: Martowicz, Agnieszka, et al.
Publicado: (2013)

Cyclin D1 overexpression and poor clinical outcomes in Taiwanese oral cavity squamous cell carcinoma
por: Huang, Shiang-Fu, et al.
Publicado: (2012)

Clinical Implications of FADD Gene Amplification and Protein Overexpression in Taiwanese Oral Cavity Squamous Cell Carcinomas
por: Chien, Huei-Tzu, et al.
Publicado: (2016)

Overexpression of eIF4E in colorectal cancer patients is associated with liver metastasis
por: Xu, Tao, et al.
Publicado: (2016)

EpCAM expression in primary tumour tissues and metastases: an immunohistochemical analysis
por: Spizzo, Gilbert, et al.
Publicado: (2011)

The Prognostic Significance of Eukaryotic Translation Initiation Factors (eIFs) in Endometrial Cancer
por: Smolle, Maria Anna, et al.
Publicado: (2019)

Overexpression of PFTK1 predicts resistance to chemotherapy in patients with oesophageal squamous cell carcinoma
por: Miyagaki, H, et al.
Publicado: (2012)

Effects of EpCAM overexpression on human breast cancer cell lines
por: Gostner, Johanna M, et al.
Publicado: (2011)

Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces ATF4 translation through delayed re-initiation
por: Kozel, Caitlin, et al.
Publicado: (2016)

eIF2Bδ blocks the integrated stress response and maintains eIF2B activity and cancer metastasis by overexpression in breast cancer stem cells
por: Gupta, Malavika, et al.
Publicado: (2023)

High STAT1 mRNA levels but not its tyrosine phosphorylation are associated with macrophage infiltration and bad prognosis in breast cancer
por: Tymoszuk, Piotr, et al.
Publicado: (2014)

The progress of protein synthesis factors eIFs, eEFs and eRFs in inflammatory bowel disease and colorectal cancer pathogenesis
por: Huang, Conggai, et al.
Publicado: (2022)

Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans
por: Cattie, Douglas J., et al.
Publicado: (2016)

eIF3 Interacts with Selenoprotein mRNAs
por: Hayek, Hassan, et al.
Publicado: (2022)

A Profound Basic Characterization of eIFs in Gliomas: Identifying eIF3I and 4H as Potential Novel Target Candidates in Glioma Therapy
por: Krassnig, Stefanie, et al.
Publicado: (2021)

Neuroimmune Consequences of eIF4E Phosphorylation on Chemotherapy-Induced Peripheral Neuropathy
por: Agalave, Nilesh M., et al.
Publicado: (2021)

Radiotherapy, Chemotherapy and Immunotherapy—Current Practice and Future Perspectives for Recurrent/Metastatic Oral Cavity Squamous Cell Carcinoma
por: Melo-Alvim, Cecília, et al.
Publicado: (2022)

Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instability
por: Chen, Muhan, et al.
Publicado: (2011)

EIF4EBP1 Overexpression Is Associated with Poor Survival and Disease Progression in Patients with Hepatocellular Carcinoma
por: Cha, Yin-Lian, et al.
Publicado: (2015)

Overexpression of eIF3D in Lung Adenocarcinoma Is a New Independent Prognostic Marker of Poor Survival
por: Wang, Dan, et al.
Publicado: (2019)

Prognostic and functional roles of EIF4G1 in lung squamous cell carcinoma
por: Bai, Baoxin, et al.
Publicado: (2023)

In vitro and in vivo silencing of plasmodial dhs and eIf-5a genes in a putative, non-canonical RNAi-related pathway
por: Schwentke, Andreas, et al.
Publicado: (2012)

An eIF for proliferation
por: LeBrasseur, Nicole
Publicado: (2008)

The Initiation Factors eIF2, eIF2A, eIF2D, eIF4A, and eIF4G Are Not Involved in Translation Driven by Hepatitis C Virus IRES in Human Cells
por: González-Almela, Esther, et al.
Publicado: (2018)

Translation of Sindbis Subgenomic mRNA is Independent of eIF2, eIF2A and eIF2D
por: Sanz, Miguel Angel, et al.
Publicado: (2017)

eIF4B, eIF4G and RNA regulate eIF4A activity in translation initiation by modulating the eIF4A conformational cycle
por: Harms, Ulf, et al.
Publicado: (2014)

Basaloid Squamous Cell Carcinoma in Nasal Cavity
por: Lee, Joong Seob, et al.
Publicado: (2009)

Preoperative concurrent chemotherapy with S-1 and radiotherapy for locally advanced squamous cell carcinoma of the oral cavity: Phase I trial
por: Harada, Hiroyuki, et al.
Publicado: (2010)

Induction chemotherapy in head and neck squamous cell carcinoma of the paranasal sinus and nasal cavity: a role in organ preservation
por: Ock, Chan-Young, et al.
Publicado: (2016)

Second primary squamous cell carcinoma of nasal cavity after successful curative radiotherapy and chemotherapy of cancer of the cavum (UCNT)()
por: Amal, Lahfidi, et al.
Publicado: (2022)

Interactome Mapping of eIF3A in a Colon Cancer and an Immortalized Embryonic Cell Line Using Proximity-Dependent Biotin Identification
por: Vo, Diep-Khanh, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0l29kg5keglcsevbs0540racs1