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The association between epicardial fat thickness in echocardiography and coronary restenosis in drug eluting stents
BACKGROUND: The association between epicardial fat and coronary in-stent restenosis has not been evaluated. The objective of the present study was to evaluate the relationship of echocardiographic epicardial fat thickness (EFT) with restenosis in drug eluting stents (DES). METHODS: In this study, 11...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347840/ https://www.ncbi.nlm.nih.gov/pubmed/22577439 |
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author | Nikaeen, Fariborz Pourmoghadas, Masoud Shemirani, Hasan Ahmad Mirdamadi, Seid Akbari, Mojtaba |
author_facet | Nikaeen, Fariborz Pourmoghadas, Masoud Shemirani, Hasan Ahmad Mirdamadi, Seid Akbari, Mojtaba |
author_sort | Nikaeen, Fariborz |
collection | PubMed |
description | BACKGROUND: The association between epicardial fat and coronary in-stent restenosis has not been evaluated. The objective of the present study was to evaluate the relationship of echocardiographic epicardial fat thickness (EFT) with restenosis in drug eluting stents (DES). METHODS: In this study, 117 patients who underwent coronary angiography due to recurrent clinical symptoms or findings of non-invasive cardiac tests one year after stent implantation were selected. According to angiographic results, they were divided into two groups, 65 patients with in-stent restenosis (case group) and 52 patients without such finding (control group). EFT was measured perpendicularly on the free wall of the right ventricle at the end of systole in two echocardiographic views (parasternal short and long axis) at least in three cardiac cycles. The average of obtained values was determined and recorded as EFT. Furthermore, the history of hypertension, smoking and diabetes, age and sex were investigated and body mass index (BMI) of each patient was also calculated. RESULTS: There were no significant differences in the baseline characteristics (P=0.812). Patients with in-stent restenosis did not have statistically significant difference (4.6±1.8 mm) in EFT compared to subjects with patent stents (4.5±1.8 mm; P=0.88). The above results were also confirmed using multiple linear regressions. No significant correlation was found between EFT and other clinical variables (P >0.05). CONCLUSION: In this selected population, the risk of restenosis was not correlated with epicardial fat thickness. Future studies for determining the role of epicardial fat in development of in-stent restenosis are warranted. |
format | Online Article Text |
id | pubmed-3347840 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-33478402012-05-10 The association between epicardial fat thickness in echocardiography and coronary restenosis in drug eluting stents Nikaeen, Fariborz Pourmoghadas, Masoud Shemirani, Hasan Ahmad Mirdamadi, Seid Akbari, Mojtaba ARYA Atheroscler Original Article BACKGROUND: The association between epicardial fat and coronary in-stent restenosis has not been evaluated. The objective of the present study was to evaluate the relationship of echocardiographic epicardial fat thickness (EFT) with restenosis in drug eluting stents (DES). METHODS: In this study, 117 patients who underwent coronary angiography due to recurrent clinical symptoms or findings of non-invasive cardiac tests one year after stent implantation were selected. According to angiographic results, they were divided into two groups, 65 patients with in-stent restenosis (case group) and 52 patients without such finding (control group). EFT was measured perpendicularly on the free wall of the right ventricle at the end of systole in two echocardiographic views (parasternal short and long axis) at least in three cardiac cycles. The average of obtained values was determined and recorded as EFT. Furthermore, the history of hypertension, smoking and diabetes, age and sex were investigated and body mass index (BMI) of each patient was also calculated. RESULTS: There were no significant differences in the baseline characteristics (P=0.812). Patients with in-stent restenosis did not have statistically significant difference (4.6±1.8 mm) in EFT compared to subjects with patent stents (4.5±1.8 mm; P=0.88). The above results were also confirmed using multiple linear regressions. No significant correlation was found between EFT and other clinical variables (P >0.05). CONCLUSION: In this selected population, the risk of restenosis was not correlated with epicardial fat thickness. Future studies for determining the role of epicardial fat in development of in-stent restenosis are warranted. Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences 2011 /pmc/articles/PMC3347840/ /pubmed/22577439 Text en © 2011 Isfahan Cardiovascular Research Center & Isfahan University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. |
spellingShingle | Original Article Nikaeen, Fariborz Pourmoghadas, Masoud Shemirani, Hasan Ahmad Mirdamadi, Seid Akbari, Mojtaba The association between epicardial fat thickness in echocardiography and coronary restenosis in drug eluting stents |
title | The association between epicardial fat thickness in echocardiography and coronary restenosis in drug eluting stents |
title_full | The association between epicardial fat thickness in echocardiography and coronary restenosis in drug eluting stents |
title_fullStr | The association between epicardial fat thickness in echocardiography and coronary restenosis in drug eluting stents |
title_full_unstemmed | The association between epicardial fat thickness in echocardiography and coronary restenosis in drug eluting stents |
title_short | The association between epicardial fat thickness in echocardiography and coronary restenosis in drug eluting stents |
title_sort | association between epicardial fat thickness in echocardiography and coronary restenosis in drug eluting stents |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347840/ https://www.ncbi.nlm.nih.gov/pubmed/22577439 |
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