Mutations increased overexpression of Notch1 in T-cell acute lymphoblastic leukemia

BACKGROUND: The Notch signaling pathway is crucial in T-cell development, Notch1 mutations are frequently present in T-cell acute lymphoblastic leukemia (T-ALL). To investigate the feature of Notch1 mutation and its corresponding expression level in Chinese patients with T-ALL, detection of mutation...

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Detalles Bibliográficos
Autores principales: Lin, Chunlan, Zheng, Haitao, Wang, Chunyan, Yang, Lijian, Chen, Shaohua, Li, Bo, Zhou, Yubing, Tan, Huo, Li, Yangqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347979/
https://www.ncbi.nlm.nih.gov/pubmed/22480166
http://dx.doi.org/10.1186/1475-2867-12-13

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