Cargando…

Exploring drug combinations in genetic interaction network

BACKGROUND: Drug combination that consists of distinctive agents is an attractive strategy to combat complex diseases and has been widely used clinically with improved therapeutic effects. However, the identification of efficacious drug combinations remains a non-trivial and challenging task due to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yin-Ying, Xu, Ke-Jia, Song, Jiangning, Zhao, Xing-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348050/ https://www.ncbi.nlm.nih.gov/pubmed/22595004 http://dx.doi.org/10.1186/1471-2105-13-S7-S7

Ejemplares similares

The drug cocktail network
por: Xu, Ke-Jia, et al.
Publicado: (2012)

Exploring hierarchical and overlapping modular structure in the yeast protein interaction network
por: Liu, Changning, et al.
Publicado: (2010)

Exploring biological interaction networks with tailored weighted quasi-bicliques
por: Chang, Wen-Chieh, et al.
Publicado: (2012)

A quantitative analysis of monochromaticity in genetic interaction networks
por: Hsu, Chien-Hsiang, et al.
Publicado: (2011)

Global multiple protein-protein interaction network alignment by combining pairwise network alignments
por: Dohrmann, Jakob, et al.
Publicado: (2015)

The exploration of network motifs as potential drug targets from post-translational regulatory networks
por: Zhang, Xiao-Dong, et al.
Publicado: (2016)

Exploration and comparison of methods for combining population- and family-based genetic association using the Genetic Analysis Workshop 17 mini-exome
por: Fardo, David W, et al.
Publicado: (2011)

Assessing and predicting protein interactions by combining manifold embedding with multiple information integration
por: Lei, Ying-Ke, et al.
Publicado: (2012)

Use of Bayesian networks to dissect the complexity of genetic disease: application to the Genetic Analysis Workshop 17 simulated data
por: Kang, Jia, et al.
Publicado: (2011)

Network-guided interaction mining for the blood pressure phenotype of unrelated individuals in genetic analysis workshop 19
por: Lo, Adeline, et al.
Publicado: (2016)

A systems biology approach to identify effective cocktail drugs
por: Wu, Zikai, et al.
Publicado: (2010)

Assessing the utility of gene co-expression stability in combination with correlation in the analysis of protein-protein interaction networks
por: Patil, Ashwini, et al.
Publicado: (2011)

Analysis of genetic and nongenetic factors influencing triglycerides-lowering drug effects based on paired observations
por: Xu, Zheng, et al.
Publicado: (2018)

On finite-horizon control of genetic regulatory networks with multiple hard-constraints
por: Yang, Cong, et al.
Publicado: (2010)

Exploring Spanish health social media for detecting drug effects
por: Segura-Bedmar, Isabel, et al.
Publicado: (2015)

Resolving anaphoras for the extraction of drug-drug interactions in pharmacological documents
por: Segura-Bedmar, Isabel, et al.
Publicado: (2010)

Ontology integration to identify protein complex in protein interaction networks
por: Xu, Bo, et al.
Publicado: (2011)

Combining active learning and semi-supervised learning techniques to extract protein interaction sentences
por: Song, Min, et al.
Publicado: (2011)

cisPath: an R/Bioconductor package for cloud users for visualization and management of functional protein interaction networks
por: Wang, Likun, et al.
Publicado: (2015)

Unraveling genetic regulatory networks of mammalian retroelements
por: Ramos, Kenneth S
Publicado: (2009)

An overlapping module identification method in protein-protein interaction networks
por: Wang, Xuesong, et al.
Publicado: (2012)

Network analysis of drug effect on triglyceride-associated DNA methylation
por: Lim, Elise, et al.
Publicado: (2018)

Core and periphery structures in protein interaction networks
por: Luo, Feng, et al.
Publicado: (2009)

Generation and application of drug indication inference models using typed network motif comparison analysis
por: Choi, Jaejoon, et al.
Publicado: (2013)

Discovering patterns in drug-protein interactions based on their fingerprints
por: Luo, Weimin, et al.
Publicado: (2012)

Joint clustering of protein interaction networks through Markov random walk
por: Wang, Yijie, et al.
Publicado: (2014)

Artificial neural networks for linkage analysis of quantitative gene expression phenotypes and evaluation of gene × gene interactions
por: Liu, Ying, et al.
Publicado: (2007)

Deciphering the genetic control of innate and adaptive immune responses in pig: a combined genetic and genomic study
por: Flori, Laurence, et al.
Publicado: (2011)

A linguistic rule-based approach to extract drug-drug interactions from pharmacological documents
por: Segura-Bedmar, Isabel, et al.
Publicado: (2011)

Dynamical modeling of uncertain interaction-based genomic networks
por: Mohsenizadeh, Daniel N, et al.
Publicado: (2015)

Building the process-drug–side effect network to discover the relationship between biological Processes and side effects
por: Lee, Sejoon, et al.
Publicado: (2011)

Combined linkage and family-based association analysis improves candidate gene detection in Genetic Analysis Workshop 18 simulation data
por: Li, Yi, et al.
Publicado: (2014)

Pathway-based joint effects analysis of rare genetic variants using Genetic Analysis Workshop 17 exon sequence data
por: Hu, Pingzhao, et al.
Publicado: (2011)

Haplotype-sharing analysis using Mantel statistics for combined genetic effects
por: Beckmann, Lars, et al.
Publicado: (2005)

Scalable high-throughput identification of genetic targets by network filtering
por: Bevilacqua, Vitoantonio, et al.
Publicado: (2013)

Constructing a robust protein-protein interaction network by integrating multiple public databases
por: Martha, Venkata-Swamy, et al.
Publicado: (2011)

Prediction of protein-protein interactions from amino acid sequences with ensemble extreme learning machines and principal component analysis
por: You, Zhu-Hong, et al.
Publicado: (2013)

The role of exon shuffling in shaping protein-protein interaction networks
por: Cancherini, Douglas V, et al.
Publicado: (2010)

Application of Bayesian networks to GAW20 genetic and blood lipid data
por: Howey, Richard A. J., et al.
Publicado: (2018)

Differential reconstructed gene interaction networks for deriving toxicity threshold in chemical risk assessment
por: Yang, Yi, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_4p2kfqvdm7g5v0p6tse869d3k5