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Repeated allergen exposure reduce early phase airway response and leukotriene release despite upregulation of 5-lipoxygenase pathways

BACKGROUND: Allergen induced early phase airway response and airway plasma exudation are predominantly mediated by inflammatory mast cell mediators including histamine, cysteinyl leukotrienes (cysLTs) and thromboxane A2 (TXA2). The aim of the present study was to evaluate whether repeated allergen e...

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Detalles Bibliográficos
Autores principales:	Cui, Zhi-Hua, Rådinger, Madeleine, Sjöstrand, Margareta, Lötvall, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348058/ https://www.ncbi.nlm.nih.gov/pubmed/22439792 http://dx.doi.org/10.1186/2045-7022-2-7

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