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Resident CD141 (BDCA3)(+) dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation
Human skin immune homeostasis, and its regulation by specialized subsets of tissue-residing immune sentinels, is poorly understood. In this study, we identify an immunoregulatory tissue-resident dendritic cell (DC) in the dermis of human skin that is characterized by surface expression of CD141, CD1...
Autores principales: | Chu, Chung-Ching, Ali, Niwa, Karagiannis, Panagiotis, Di Meglio, Paola, Skowera, Ania, Napolitano, Luca, Barinaga, Guillermo, Grys, Katarzyna, Sharif-Paghaleh, Ehsan, Karagiannis, Sophia N., Peakman, Mark, Lombardi, Giovanna, Nestle, Frank O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348099/ https://www.ncbi.nlm.nih.gov/pubmed/22547651 http://dx.doi.org/10.1084/jem.20112583 |
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