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Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis

Rheumatoid arthritis is a destructive arthropathy characterized by chronic synovial inflammation that imposes a substantial socioeconomic burden. Under the influence of the proinflammatory milieu, synovial fibroblasts (SFs), the main effector cells in disease pathogenesis, become activated and hyper...

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Detalles Bibliográficos
Autores principales: Nikitopoulou, Ioanna, Oikonomou, Nikos, Karouzakis, Emmanuel, Sevastou, Ioanna, Nikolaidou-Katsaridou, Nefeli, Zhao, Zhenwen, Mersinias, Vassilis, Armaka, Maria, Xu, Yan, Masu, Masayuki, Mills, Gordon B., Gay, Steffen, Kollias, George, Aidinis, Vassilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348105/
https://www.ncbi.nlm.nih.gov/pubmed/22493518
http://dx.doi.org/10.1084/jem.20112012