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Prion-like spread of protein aggregates in neurodegeneration

Protein misfolding is common to most neurodegenerative diseases, including Alzheimer’s and Parkinson’s diseases. Recent work using animal models with intracellular α-synuclein and tau inclusions adds decisively to a growing body of evidence that misfolded protein aggregates can induce a self-perpetu...

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Detalles Bibliográficos
Autores principales:	Polymenidou, Magdalini, Cleveland, Don W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Minireview
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348110/ https://www.ncbi.nlm.nih.gov/pubmed/22566400 http://dx.doi.org/10.1084/jem.20120741

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