Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma

Host resistance to viral infection requires type I (α/β) and II (γ) interferon (IFN) production. Another important defense mechanism is the degradative activity of macroautophagy (herein autophagy), mediated by the coordinated action of evolutionarily conserved autophagy proteins (Atg). We show that...

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Detalles Bibliográficos
Autores principales: Hwang, Seungmin, Maloney, Nicole S., Bruinsma, Monique W., Goel, Gautam, Duan, Erning, Zhang, Lei, Shrestha, Bimmi, Diamond, Michael S., Dani, Adish, Sosnovtsev, Stanislav V., Green, Kim Y., Lopez-Otin, Carlos, Xavier, Ramnik J., Thackray, Larissa B., Virgin, Herbert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348177/
https://www.ncbi.nlm.nih.gov/pubmed/22520467
http://dx.doi.org/10.1016/j.chom.2012.03.002

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