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Growth inhibition induced by antiprogestins RU-38486, ORG-31710, and CDB-2914 in ovarian cancer cells involves inhibition of cyclin dependent kinase 2

Antiprogestins have been largely utilized in reproductive medicine, yet their repositioning for oncologic use is rapidly emerging. In this study we investigated the molecular mediators of the anti-ovarian cancer activity of the structurally related antiprogestins RU-38486, ORG-31710 and CDB-2914. We...

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Detalles Bibliográficos
Autores principales: Goyeneche, Alicia A., Seidel, Erin E., Telleria, Carlos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348464/
https://www.ncbi.nlm.nih.gov/pubmed/21424700
http://dx.doi.org/10.1007/s10637-011-9655-z