The journey of resveratrol from yeast to human

The natural polyphenolic compound resveratrol was first discovered in the 1940s. In the recent years, this compound received renewed interest as several findings implicated resveratrol as a potent SIRT1 activator capable of mimicking the effects of calorie restriction, and regulating longevity in lo...

Descripción completa

Detalles Bibliográficos
Autores principales: Timmers, Silvie, Auwerx, Johan, Schrauwen, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348475/
https://www.ncbi.nlm.nih.gov/pubmed/22436213
_version_ 1782232389924159488
author Timmers, Silvie
Auwerx, Johan
Schrauwen, Patrick
author_facet Timmers, Silvie
Auwerx, Johan
Schrauwen, Patrick
author_sort Timmers, Silvie
collection PubMed
description The natural polyphenolic compound resveratrol was first discovered in the 1940s. In the recent years, this compound received renewed interest as several findings implicated resveratrol as a potent SIRT1 activator capable of mimicking the effects of calorie restriction, and regulating longevity in lower organisms. Given the worldwide increase in age-related metabolic diseases the beneficial effects of resveratrol on metabolism and healthy aging in humans are currently a topic of intense investigation.
format Online
Article
Text
id pubmed-3348475
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Impact Journals LLC
record_format MEDLINE/PubMed
spelling pubmed-33484752012-05-14 The journey of resveratrol from yeast to human Timmers, Silvie Auwerx, Johan Schrauwen, Patrick Aging (Albany NY) Review The natural polyphenolic compound resveratrol was first discovered in the 1940s. In the recent years, this compound received renewed interest as several findings implicated resveratrol as a potent SIRT1 activator capable of mimicking the effects of calorie restriction, and regulating longevity in lower organisms. Given the worldwide increase in age-related metabolic diseases the beneficial effects of resveratrol on metabolism and healthy aging in humans are currently a topic of intense investigation. Impact Journals LLC 2012-03-12 /pmc/articles/PMC3348475/ /pubmed/22436213 Text en Copyright: © 2012 Timmers et al. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
spellingShingle Review
Timmers, Silvie
Auwerx, Johan
Schrauwen, Patrick
The journey of resveratrol from yeast to human
title The journey of resveratrol from yeast to human
title_full The journey of resveratrol from yeast to human
title_fullStr The journey of resveratrol from yeast to human
title_full_unstemmed The journey of resveratrol from yeast to human
title_short The journey of resveratrol from yeast to human
title_sort journey of resveratrol from yeast to human
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348475/
https://www.ncbi.nlm.nih.gov/pubmed/22436213
work_keys_str_mv AT timmerssilvie thejourneyofresveratrolfromyeasttohuman
AT auwerxjohan thejourneyofresveratrolfromyeasttohuman
AT schrauwenpatrick thejourneyofresveratrolfromyeasttohuman
AT timmerssilvie journeyofresveratrolfromyeasttohuman
AT auwerxjohan journeyofresveratrolfromyeasttohuman
AT schrauwenpatrick journeyofresveratrolfromyeasttohuman

Ejemplares similares