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Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging
Cell cycle arrest is not yet senescence. When the cell cycle is arrested, an inappropriate growth-promotion converts an arrest into senescence (geroconversion). By inhibiting the growth-promoting mTOR pathway, rapamycin decelerates geroconversion of the arrested cells. And as a striking example, whi...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348476/ https://www.ncbi.nlm.nih.gov/pubmed/22394614 |