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TCR Nanoclusters as the Framework for Transmission of Conformational Changes and Cooperativity
Increasing evidence favors the notion that, before triggering, the T cell antigen receptor (TCR) forms nanometer-scale oligomers that are called nanoclusters. The organization of the TCR in pre-existing oligomers cannot be ignored when analyzing the properties of ligand (pMHC) recognition and signal...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Research Foundation
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348506/ https://www.ncbi.nlm.nih.gov/pubmed/22582078 http://dx.doi.org/10.3389/fimmu.2012.00115 |