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TCR Nanoclusters as the Framework for Transmission of Conformational Changes and Cooperativity

Increasing evidence favors the notion that, before triggering, the T cell antigen receptor (TCR) forms nanometer-scale oligomers that are called nanoclusters. The organization of the TCR in pre-existing oligomers cannot be ignored when analyzing the properties of ligand (pMHC) recognition and signal...

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Detalles Bibliográficos
Autores principales:	Blanco, Raquel, Alarcón, Balbino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348506/ https://www.ncbi.nlm.nih.gov/pubmed/22582078 http://dx.doi.org/10.3389/fimmu.2012.00115

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